Krommes Kasper, Bjerre Amalie, Thorborg Kristian, Nielsen Mathias Fabricius, Hölmich Per
Sports Orthopedic Research Center-Copenhagen, Orthopedic Department, Amager-Hvidovre, Copenhagen University Hospital, Copenhagen, Denmark.
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Sports Med. 2025 May 29. doi: 10.1007/s40279-025-02214-5.
Osgood-Schlatter has, until recently, been suggested to be a benign condition, affecting adolescents in terms of knee pain and decreased sports participation during growth, with no long-term consequences seen later in adulthood.
The objectives of this study were to describe the long-term knee health in adults with a history of Osgood-Schlatter, compare these findings with healthy population estimates, and investigate if explanatory variables are associated with current knee health.
The Danish Patient Registry identified patients ≥ 18 years diagnosed with adolescent Osgood-Schlatter in hospitals during 1977-2020. All cases participated in a survey about knee-related health and comorbidities. Existing literature was sourced for the healthy population estimates for comparisons. Explanatory variables were recalled Osgood-Schlatter duration, pain levels, restrictions, and current tibial tubercle prominence.
Of 1281 identified patients, 400 responded. Most reported having a current bony prominence of the tibial tubercle (85%) and sustained pain/problems from the same area (73%). Compared with healthy population estimates, Osgood-Schlatter cases scored lower on the Knee Injury and Osteoarthritis Outcome Score on all subscales (p < 0.05), particularly for "sport/rec" and "quality of life" (Cohen's d > 0.8). Similarly, cases exhibited a large risk of "jumper's knee" (odds ratio: 70.4 [95% confidence intervals, CI: 32.9; 155.0], p < 0.0001). Symptom duration and pain levels were negatively associated with several outcomes (p < 0.05).
Adults with a history of Osgood-Schlatter have significantly worse long-term knee health than what is observed from healthy population estimates. Recalled longer symptom duration and higher pain levels were associated with worse current knee health. This information should potentially guide management to maintain knee health over time, as the condition is not always as benign and self-limiting as previously thought.
NCT04313621.
直到最近，奥斯古德-施拉特病一直被认为是一种良性疾病，在青少年生长期间会导致膝关节疼痛并减少体育活动参与度，但成年后未见长期后果。
本研究的目的是描述有奥斯古德-施拉特病史的成年人的长期膝关节健康状况，将这些结果与健康人群的估计值进行比较，并调查解释变量是否与当前膝关节健康状况相关。
丹麦患者登记处识别出1977年至2020年期间在医院被诊断为青少年奥斯古德-施拉特病的18岁及以上患者。所有病例都参与了一项关于膝关节相关健康状况和合并症的调查。从现有文献中获取健康人群的估计值用于比较。解释变量包括回忆起的奥斯古德-施拉特病持续时间、疼痛程度、活动受限情况以及当前胫骨结节突出情况。
在1281名识别出的患者中，400人做出了回应。大多数人报告目前胫骨结节有骨性突出（85%），且同一部位持续疼痛/存在问题（73%）。与健康人群的估计值相比，奥斯古德-施拉特病病例在膝关节损伤和骨关节炎结局评分的所有子量表上得分更低（p < 0.05），尤其是在“运动/娱乐”和“生活质量”方面（科恩d值> 0.8）。同样，病例出现“跳跃膝”的风险很大（优势比：70.4 [95%置信区间，CI：32.9；155.0]，p < 0.0001）。症状持续时间和疼痛程度与多个结局呈负相关（p < 0.05）。
有奥斯古德-施拉特病史的成年人的长期膝关节健康状况明显比健康人群估计的情况更差。回忆起的症状持续时间越长和疼痛程度越高，与当前膝关节健康状况越差相关。随着时间的推移，这些信息可能有助于指导维持膝关节健康的管理，因为这种疾病并不总是像以前认为的那样是良性和自限性的。
NCT04313621
