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人群中艾滋病毒病毒抑制的趋势：一项纵向分析。

Trends in population HIV viral suppression: a longitudinal analysis.

作者信息

Otto Margot, Okango Elphas, Mee Paul, Dobra Adrian, Tram Khai Hoan, Gareta Dickman, Otambo Wilfred, Moyo Reuben, Sereo Tumelo, Blose Ntombifuthi, Letoao Nthoesele Shoeshoe, Mupanguri Letitsia, Mwambi Henry, Herbst Kobus, Tanser Frank

机构信息

Centre for Epidemic Response and Innovation, School for Data Science and Computational Thinking.

South African Centre for Epidemiological Modelling and Analysis (SACEMA), Stellenbosch University, Stellenbosch.

出版信息

AIDS. 2025 Jul 1;39(8):1088-1092. doi: 10.1097/QAD.0000000000004183. Epub 2025 May 29.

DOI:10.1097/QAD.0000000000004183
PMID:40440236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12144545/
Abstract

This study examines trends in HIV viral suppression and the impact of age and sex on suppression rates in a rural KwaZulu-Natal (KZN) population-based cohort from 2011 to 2023. Population viral suppression improved over time, peaking at 71% for men and 79% for women in 2022, but declined in 2023 possibly due to COVID-19 disruptions. Viral suppression rates were substantially lower than reported regional estimates for KZN. Disparities among younger males highlight the need for interventions to achieve UNAIDS 95-95-95 targets.

摘要

本研究调查了2011年至2023年夸祖鲁-纳塔尔省（KZN）农村地区基于人群的队列中艾滋病毒病毒抑制的趋势以及年龄和性别对抑制率的影响。总体病毒抑制情况随时间有所改善，2022年男性达到71%、女性达到79%的峰值，但在2023年有所下降，这可能是由于新冠疫情造成的干扰。病毒抑制率远低于KZN地区报告的估计数。年轻男性之间的差异凸显了为实现联合国艾滋病规划署95-95-95目标而采取干预措施的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b393/12144545/f3d158001b85/aids-39-1088-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b393/12144545/f3d158001b85/aids-39-1088-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b393/12144545/f3d158001b85/aids-39-1088-g001.jpg

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南非夸祖鲁-纳塔尔省 HIV 病毒抑制率上升：2018 年和 2013 年基于社区的横断面调查。还有哪些工作要做？
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Determinants of viral suppression among adolescents on antiretroviral treatment in Ehlanzeni district, South Africa: a cross-sectional analysis.南非埃兰兹尼地区接受抗逆转录病毒治疗的青少年病毒抑制的决定因素：一项横断面分析。
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Proc Natl Acad Sci U S A. 2021 Jul 13;118(28). doi: 10.1073/pnas.2013164118.
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