McKenzie E H, Volkert W A, Holmes R A
Int J Nucl Med Biol. 1985;12(2):133-4. doi: 10.1016/0047-0740(85)90168-8.
The biodistribution of [14C]3,3'-(1,3-propanediyldiimino)-bis(3-methy 1-2-butanone)-dioxime, [( 14C]PnAO) was determined in anesthetized rats. The results of this study show that there is no significant brain accumulation or retention of the uncomplexed ligand in the brain.
在麻醉大鼠中测定了[14C]3,3'-(1,3 - 丙二基二亚氨基)-双(3 - 甲基 - 2 - 丁酮)-二肟([14C]PnAO)的生物分布。本研究结果表明,未络合的配体在脑中没有显著的蓄积或滞留。