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超声引导下经皮腹横肌肌间沟阻滞与超声引导下骶管阻滞用于小儿开放性肾手术的比较:一项随机试验。

Ultrasound-guided trans-incisional quadratus lumborum block versus ultrasound-guided caudal analgesia in pediatric open renal surgery: a randomized trial.

机构信息

Department of Anesthesiology, Intensive Care and Pain Management, Faculty of Medicine, Ain-Shams University, Cairo, Egypt.

Department of Urology, Menoufia University, Cairo, Egypt.

出版信息

Korean J Anesthesiol. 2023 Oct;76(5):471-480. doi: 10.4097/kja.22774. Epub 2023 Jan 26.

Abstract

BACKGROUND

The caudal route is a common approach for postoperative analgesia; however, it is associated with limited duration of action. The quadratus lumborum block (QLB) may produce prolonged postoperative analgesia. Therefore, this study aimed to compare the postoperative analgesic efficacy of the ultrasound-guided caudal block with that of the ultrasound-guided transincisional QLB (TiQLB) in pediatric patients undergoing open renal surgery.

METHODS

Forty patients of both sexes, aged 2-11 years, were randomly assigned to receive either caudal analgesia with 1.25 ml/kg of bupivacaine 0.2% (Caudal group; n = 20) or a QLB with 0.5 ml/kg of bupivacaine 0.2% (TiQLB group; n = 20) in addition to standard general anesthesia. Time to first analgesia was the primary outcome. Total analgesic consumption in the first 24 h postoperatively, pain scores, and the incidence of side effects were the secondary outcomes.

RESULTS

The mean time to first analgesic requirement was significantly longer in the TiQLB group than in the Caudal group (18.8 ± 5.1 vs. 6.7 ± 0.7 h, P < 0.001). Total ketorolac consumption and pain scores were significantly lower in the TiQLB group (P < 0.001). A few cases of mild postoperative nausea and vomiting were noted among patients in both groups; however, the difference was not statistically significant. No incidence of pruritus, shivering, or respiratory depression was noted.

CONCLUSIONS

Analgesia after the ultrasound-guided TiQLB with bupivacaine was superior to that after the ultrasound-guided caudal block, with similar side effects.

摘要

背景

骶管阻滞是一种常用的术后镇痛方法,但作用时间有限。腹横肌平面阻滞(QLB)可能产生长时间的术后镇痛。因此,本研究旨在比较超声引导下骶管阻滞与超声引导下经皮 QLB(TiQLB)在小儿开放性肾手术中的术后镇痛效果。

方法

40 例 2-11 岁的男女患儿随机分为接受 1.25 ml/kg 0.2%布比卡因的骶管阻滞(Caudal 组,n=20)或 0.5 ml/kg 0.2%布比卡因的 TiQLB(TiQLB 组,n=20),并加用标准全身麻醉。首次镇痛时间是主要结局。术后 24 小时内的总镇痛消耗、疼痛评分和不良反应发生率是次要结局。

结果

TiQLB 组首次需要镇痛的平均时间明显长于 Caudal 组(18.8±5.1 vs. 6.7±0.7 h,P<0.001)。TiQLB 组的总酮咯酸消耗和疼痛评分明显较低(P<0.001)。两组患者均有少数轻度术后恶心和呕吐病例,但差异无统计学意义。未发现瘙痒、寒战或呼吸抑制。

结论

超声引导下 TiQLB 用布比卡因的镇痛效果优于超声引导下骶管阻滞,且不良反应相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d795/10562062/bdcc9ad10ffe/kja-22774f1.jpg

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