Meeks Karlijn A C, Agyemang Charles
Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, 670 W. Baltimore Street, HSF III 4061, Baltimore, MD, 21201, USA.
Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, USA.
Curr Atheroscler Rep. 2025 May 30;27(1):59. doi: 10.1007/s11883-025-01307-w.
To provide an overview of the current available evidence on the burden of cardiovascular diseases (CVD) among African migrants, including its risk factors, underlying mechanisms, and prevention and treatment efforts, while highlighting critical gaps in knowledge.
The CVD burden is high among most African migrant populations. Underlying mechanisms for the high CVD burden include various pre- and post-migration factors, genetics, and epigenetics. Studies increasingly show substantial variation in CVD burden among African migrants across factors such as country of origin, host country, reason for migration, duration of stay, sex, and age. This variation is also observed among CVD risk factors and requires tailored prevention and treatment efforts. To fill critical gaps in knowledge, future studies need to recruit among diverse African migrant populations, in various high-income countries, using standardized methodologies with a focus on longitudinal designs, and integrating lifestyle, sociocultural, environmental, and genetic factors.
概述目前关于非洲移民心血管疾病(CVD)负担的现有证据,包括其风险因素、潜在机制以及预防和治疗措施,同时突出知识方面的关键差距。
大多数非洲移民人群的心血管疾病负担较高。心血管疾病负担高的潜在机制包括移民前后的各种因素、遗传学和表观遗传学。研究越来越多地表明,非洲移民的心血管疾病负担因原籍国、东道国、移民原因、停留时间、性别和年龄等因素存在很大差异。这种差异在心血管疾病风险因素中也有体现,需要采取针对性的预防和治疗措施。为填补知识方面的关键差距,未来的研究需要在不同高收入国家的多样化非洲移民人群中进行招募,采用标准化方法,重点是纵向设计,并整合生活方式、社会文化、环境和遗传因素。