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脊髓损伤研究领域中的性别映射:文献计量分析与研究框架

Mapping sex and gender in the landscape of spinal cord injury research: a bibliometric analysis and research framework.

作者信息

Stojic Stevan, Affolter Serena, Stadler Gertraud, Missmer Stacey A, Pannek Juergen, Stoyanov Jivko, Eriks-Hoogland Inge, Lüscher Janina, Glisic Marija

机构信息

Swiss Paraplegic Research, Nottwil, Switzerland.

Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.

出版信息

Spinal Cord. 2025 May 29. doi: 10.1038/s41393-025-01089-7.

DOI:10.1038/s41393-025-01089-7
PMID:40442490
Abstract

STUDY DESIGN

Bibliometric analysis and conceptual framework.

OBJECTIVES

To provide a framework for prioritizing sex/gender research in the field of spinal cord injury (SCI), which can help inform and develop future research directions benefiting both women and men affected by SCI.

SETTING

Not applicable METHODS: We searched the Web of Science Core Collection to identify relevant articles. Data was analyzed using the Bibliometrix and VoSviewer tools to provide a macroscopic overview of sex/gender research trends in the field of SCI research. A framework was developed based on the results of bibliometric analyses and literature scoping, engaging professionals with backgrounds in gender medicine, translational medicine, psychology, clinical epidemiology, SCI, and endocrinology.

RESULTS

A total of 1031 documents were included in the analyses. We observed a steady increase in sex/gender related research from 2012, with an annual growth rate of 9.64%. Rehabilitation, epidemiology, obesity, depression, and sex hormones were identified as fundamental and critical topics for advancing sex and gender research in the context of SCI. Among a randomly selected articles, a significant proportion of studies interchangeably used the terms sex and gender. Therefore, we discuss the key overarching themes and terminology that are essential for any study exploring the relevance of sex and gender in health research. We developed a three-step research framework for considering and incorporating sex and gender in research, using SCI as a case in point.

CONCLUSION

The major principles in current paper can benefit everyone interested in studying sex/gender in the context of health in complex and disabling conditions.

摘要

研究设计

文献计量分析与概念框架。

目的

为脊髓损伤(SCI)领域的性别研究确定优先顺序提供一个框架,这有助于为未来的研究方向提供信息并加以发展,使受SCI影响的男性和女性都能受益。

背景

不适用

方法

我们检索了科学网核心合集以识别相关文章。使用文献计量学和VOSviewer工具对数据进行分析,以提供SCI研究领域性别研究趋势的宏观概述。基于文献计量分析和文献综述的结果,与具有性别医学、转化医学、心理学、临床流行病学、SCI和内分泌学背景的专业人员共同制定了一个框架。

结果

分析共纳入1031篇文献。我们观察到2012年以来与性别相关的研究稳步增加,年增长率为9.64%。康复、流行病学、肥胖、抑郁和性激素被确定为在SCI背景下推进性别研究的基础和关键主题。在随机挑选的文章中,很大一部分研究互换使用了“性”和“性别”这两个术语。因此,我们讨论了在任何探索性别与健康研究相关性的研究中至关重要的关键总体主题和术语。我们以SCI为例,开发了一个在研究中考虑和纳入性别的三步研究框架。

结论

本文中的主要原则可使所有对在复杂和致残状况下的健康背景中研究性别感兴趣的人受益。

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本文引用的文献

1
Gender scores in epidemiological research: methods, advantages and implications.流行病学研究中的性别评分:方法、优势及影响
Lancet Reg Health Eur. 2024 Jun 14;43:100962. doi: 10.1016/j.lanepe.2024.100962. eCollection 2024 Aug.
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A developmental framework for understanding the influence of sex and gender on health: Pediatric pain as an exemplar.理解性别对健康影响的发展框架:以儿科疼痛为例。
Neurosci Biobehav Rev. 2024 Mar;158:105546. doi: 10.1016/j.neubiorev.2024.105546. Epub 2024 Jan 24.
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Practical solutions for including sex as a biological variable (SABV) in preclinical neuropsychopharmacological research.
临床前神经精神药理学研究中纳入性别作为生物学变量(SABV)的实用解决方案。
J Neurosci Methods. 2024 Jan 1;401:110003. doi: 10.1016/j.jneumeth.2023.110003. Epub 2023 Oct 31.
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A roadmap for sex- and gender-disaggregated health research.性和性别分类健康研究的路线图。
BMC Med. 2023 Sep 13;21(1):354. doi: 10.1186/s12916-023-03060-w.
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Systematic review and meta-analysis use in the field of spinal cord injury research: A bibliometric analysis.系统评价与荟萃分析在脊髓损伤研究领域的应用:一项文献计量分析。
J Spinal Cord Med. 2025 Jan;48(1):54-64. doi: 10.1080/10790268.2023.2251205. Epub 2023 Sep 8.
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Statistical simulations show that scientists need not increase overall sample size by default when including both sexes in in vivo studies.统计模拟表明,科学家在体内研究中纳入两性时,不必默认增加总体样本量。
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Sex and Gender Reporting in Rehabilitation Research: A Commentary.康复研究中的性与性别报告:述评。
Arch Phys Med Rehabil. 2023 Aug;104(8):1356-1358. doi: 10.1016/j.apmr.2023.03.034. Epub 2023 Apr 29.
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A framework for sex, gender, and diversity analysis in research.用于研究中的性别和多样性分析的框架。
Science. 2022 Sep 30;377(6614):1492-1495. doi: 10.1126/science.abp9775. Epub 2022 Sep 29.
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Integrating Sex/Gender into Environmental Health Research: Development of a Conceptual Framework.将性/性别纳入环境健康研究:概念框架的发展。
Int J Environ Res Public Health. 2021 Nov 18;18(22):12118. doi: 10.3390/ijerph182212118.
10
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J Clin Epidemiol. 2021 Nov;139:177-190. doi: 10.1016/j.jclinepi.2021.07.015. Epub 2021 Jul 27.