Liu Sunny, Matthews Timothy A, Guardiano Megan, Mayeda Elizabeth Rose, Li Jian
University of California Los Angeles, Los Angeles, United States.
California State University Northridge, Northridge, United States.
Int J Behav Med. 2025 May 29. doi: 10.1007/s12529-025-10370-1.
Poor sleep quality is linked to increased risk for cardiometabolic complications and mortality. Previous research suggested workplace and everyday discrimination are separately linked to adverse sleep outcomes. The aim of this study is to examine the joint effects of workplace and everyday discrimination on sleep quality among middle-aged adults.
Data from the Midlife in the United States (MIDUS) study were used, with a 9-year follow-up of 1,333 individuals free from sleep disturbances at baseline. Baseline measures of workplace and everyday discrimination were collected, and the incidence of sleep disturbances was assessed at follow-up. Poisson regression was used to estimate risk ratios (RRs) and 95% confidence intervals (CIs). The synergy index was applied to evaluate whether the combined effect of both types of discrimination was greater than their individual effects.
Workplace discrimination was associated with a higher risk of sleep disturbances (adjusted RR = 1.50 [1.09, 2.06]). Everyday discrimination also increased the risk of sleep disturbances (adjusted RR= 1.38 [1.00, 1.93]). The joint effect of workplace and everyday discrimination was associated with a higher risk of sleep disturbances (adjusted RR = 1.78 [1.16, 2.72]), with synergy index suggesting an additive interaction.
Both workplace and everyday discrimination independently affect sleep quality, with an additive interaction between the two. The double burden of workplace and everyday discrimination can significantly impact sleep disturbances. Further research is needed to explore the biological mechanisms linking discrimination and sleep disturbances.
睡眠质量差与心血管代谢并发症及死亡率风险增加有关。先前的研究表明，职场歧视和日常歧视分别与不良睡眠结果相关。本研究的目的是探讨职场歧视和日常歧视对中年成年人睡眠质量的联合影响。
使用来自美国中年（MIDUS）研究的数据，对1333名基线时无睡眠障碍的个体进行了9年的随访。收集了职场歧视和日常歧视的基线测量数据，并在随访时评估了睡眠障碍的发生率。采用泊松回归估计风险比（RRs）和95%置信区间（CIs）。应用协同指数评估两种歧视的联合效应是否大于其单独效应。
职场歧视与睡眠障碍风险较高相关（调整后RR = 1.50 [1.09, 2.06]）。日常歧视也增加了睡眠障碍风险（调整后RR = 1.38 [1.00, 1.93]）。职场歧视和日常歧视的联合效应与睡眠障碍风险较高相关（调整后RR = 1.78 [1.16, 2.72]），协同指数表明存在相加交互作用。
职场歧视和日常歧视均独立影响睡眠质量，二者之间存在相加交互作用。职场歧视和日常歧视的双重负担会显著影响睡眠障碍。需要进一步研究以探索将歧视与睡眠障碍联系起来的生物学机制。
