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美国国家健康与营养检查调查(2005 - 2006年)中饮食炎症指数与过敏性鼻炎的关联

Association between the dietary inflammatory index and allergic rhinitis results from the National health and nutrition examination survey (2005-2006).

作者信息

Shen Hanchao, Liao Jie, Zhang Lan, Li Peijia, Jiang Luyun, Guo Tao, Yu Ya, Xie Hui

机构信息

Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610032, China.

Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.

出版信息

J Health Popul Nutr. 2025 May 29;44(1):179. doi: 10.1186/s41043-025-00932-0.

Abstract

BACKGROUND

Common chronic inflammatory condition known as allergic rhinitis(AR) has a major negative influence on people's health and puts a heavy strain on the world's healthcare systems. Despite the significant incidence of AR. This study aims to assess the potential link between the Dietary Inflammatory Index (DII) and the risk of developing AR.

METHODS

This study involved the analysis of data from 3,938 adult participants in the National Health and Nutrition Examination Survey (NHANES) conducted in 2005-2006. The DII score was used to evaluate the inflammatory potential of the participants' diets, and Multivariable logistic regression models were used to assess the association between DII (in tertiles) and having AR, adjusting for potential confounders. Subgroup analyses stratified by sex and Body Mass Index (BMI) were conducted to evaluate effect modification.

RESULTS

Our study demonstrated a positive correlation between the DII and the odds of AR prevalence. After adjusting for potential confounders, compared to individuals in the lowest tertile, those in the highest DII tertile had a 34% higher odds of AR prevalence.(OR 1.34, 95% CI 1.09-1.65). Furthermore, the subgroup analysis revealed a significant interaction (P < 0.05 for interaction) when stratified by sex and BMI.

CONCLUSION

These results show that a higher DII score corresponds to the odds of AR prevalence, emphasizing the possible reduction of AR risk that can be achieved by eating a diet strong in anti-inflammatory nutrients and low in pro-inflammatory foods. This study emphasizes the role that dietary choices play in managing the risk of developing AR.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

变应性鼻炎(AR)是一种常见的慢性炎症性疾病,对人们的健康有重大负面影响,并给全球医疗保健系统带来沉重负担。尽管AR的发病率很高,但本研究旨在评估饮食炎症指数(DII)与患AR风险之间的潜在联系。

方法

本研究分析了2005 - 2006年进行的美国国家健康与营养检查调查(NHANES)中3938名成年参与者的数据。DII评分用于评估参与者饮食的炎症潜力,多变量逻辑回归模型用于评估DII(按三分位数划分)与患AR之间的关联,并对潜在混杂因素进行调整。进行了按性别和体重指数(BMI)分层的亚组分析以评估效应修饰。

结果

我们的研究表明DII与AR患病率的比值之间存在正相关。在对潜在混杂因素进行调整后,与最低三分位数的个体相比,DII最高三分位数的个体患AR的几率高34%。(比值比1.34,95%置信区间1.09 - 1.65)。此外,亚组分析显示按性别和BMI分层时存在显著交互作用(交互作用P < 0.05)。

结论

这些结果表明,较高的DII评分与AR患病率的几率相对应,强调了通过食用富含抗炎营养素且低促炎食物的饮食来降低AR风险的可能性。本研究强调了饮食选择在控制患AR风险方面所起的作用。

临床试验编号

不适用。

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