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基于心电图的人工智能进展揭示多系统生物标志物。

Advances in Electrocardiogram-Based Artificial Intelligence Reveal Multisystem Biomarkers.

作者信息

Liu Xichong, Bandyopadhyay Sabyasachi, Rogers Albert J

机构信息

Department of Cardiology, Cardiovascular Institute, Stanford University School of Medicine, Stanford, USA.

出版信息

J Clin Exp Cardiolog. 2025;16(2). Epub 2025 Mar 24.

PMID:40443717
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12121951/
Abstract

As Artificial Intelligence (AI) plays an increasingly prominent role in society, its application in clinical cardiology is gaining traction by providing innovative diagnostic, prognostic, and therapeutic solutions. Electrocardiogram (ECG), as a ubiquitous diagnostic tool in cardiology, has emerged as the leading data source for Deep Learning (DL) applications. A recent study from our group used ECG-based DL model to identify cardiac wall motion abnormalities and outperformed expert human interpretation. Motivated by this work and that of many others, we aim to discuss advances, limitations, future directions, and equity considerations in DL models for ECG-based AI applications.

摘要

随着人工智能(AI)在社会中发挥着越来越突出的作用,其在临床心脏病学中的应用通过提供创新的诊断、预后和治疗解决方案而越来越受到关注。心电图(ECG)作为心脏病学中一种普遍使用的诊断工具,已成为深度学习(DL)应用的主要数据源。我们团队最近的一项研究使用基于心电图的深度学习模型来识别心脏壁运动异常,其表现优于专家的人工解读。受这项工作以及其他许多研究的启发,我们旨在讨论基于心电图的人工智能应用中深度学习模型的进展、局限性、未来方向和平等性考量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c1d/12121951/e7d6e3b58e24/nihms-2067708-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c1d/12121951/e7d6e3b58e24/nihms-2067708-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c1d/12121951/e7d6e3b58e24/nihms-2067708-f0001.jpg

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本文引用的文献

1
Identification of cardiac wall motion abnormalities in diverse populations by deep learning of the electrocardiogram.通过心电图深度学习识别不同人群的心脏壁运动异常。
NPJ Digit Med. 2025 Jan 11;8(1):21. doi: 10.1038/s41746-024-01407-y.
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A multitask deep learning model utilizing electrocardiograms for major cardiovascular adverse events prediction.一种利用心电图进行主要心血管不良事件预测的多任务深度学习模型。
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A hybrid deep learning network for automatic diagnosis of cardiac arrhythmia based on 12-lead ECG.
基于 12 导联心电图的心律失常自动诊断的混合深度学习网络。
Sci Rep. 2024 Oct 18;14(1):24441. doi: 10.1038/s41598-024-75531-w.
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Deep learning assists early-detection of hypertension-mediated heart change on ECG signals.深度学习助力基于心电图信号早期检测高血压介导的心脏变化。
Hypertens Res. 2025 Feb;48(2):681-692. doi: 10.1038/s41440-024-01938-7. Epub 2024 Oct 12.
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MDDBranchNet: A Deep Learning Model for Detecting Major Depressive Disorder Using ECG Signal.MDDBranchNet:一种基于心电图信号的深度学习模型,用于检测重度抑郁症。
IEEE J Biomed Health Inform. 2024 Jul;28(7):3798-3809. doi: 10.1109/JBHI.2024.3390847.
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Artificial intelligence-enabled ECG for left ventricular diastolic function and filling pressure.用于评估左心室舒张功能和充盈压的人工智能心电图技术
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Race, Sex, and Age Disparities in the Performance of ECG Deep Learning Models Predicting Heart Failure.种族、性别和年龄差异对心电图深度学习模型预测心力衰竭性能的影响。
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JAMA Cardiol. 2023 Dec 1;8(12):1131-1139. doi: 10.1001/jamacardio.2023.3701.
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