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肝静脉综合征:一例病例报告及文献综述

Hepatic vena cava syndrome: a case report and literature review.

作者信息

Zahid Muhammad, Es-Salim Mohammad, Moursi Moaz O, Mahmood Nabil, Elzouki Abdel-Naser

机构信息

Department of Internal Medicine, Hamad General Hospital, Doha, Qatar.

College of Medicine, QU Health, Qatar University, Doha, Qatar.

出版信息

Oxf Med Case Reports. 2025 May 28;2025(5):omaf035. doi: 10.1093/omcr/omaf035. eCollection 2025 May.

Abstract

BACKGROUND

Hepatic vena cava syndrome (HVCS) is an uncommon condition, with no prior reports from the Gulf area. In regions with limited resources, where this disease is found, there is a lack of data due to underdiagnosis. HVCS results from recurrent bacterial thrombophlebitis of the hepatic portion of the inferior vena cava (IVC), causing intimal thickening and obstruction, eventually leading to complications like liver cirrhosis and hepatocellular carcinoma.

CASE PRESENTATION

A 32-year-old Afghan refugee lady, presented with progressive abdominal distention. Initial investigations showed anemia, splenomegaly, and massive ascites. Further investigations revealed cirrhotic liver, varices, and a stenotic segment of the IVC. She was diagnosed with HVCS, underwent IVC stenting, and commenced on clopidogrel and dabigatran. Conclusion Often misdiagnosed, HVCS requires a high index of suspicion and should be considered in patients with liver cirrhosis with low socioeconomic backgrounds. Early diagnosis can prevent liver cirrhosis and hepatocellular carcinoma.

摘要

背景

肝静脉综合征(HVCS)是一种罕见病症,海湾地区此前尚无相关报道。在发现该疾病的资源有限地区,由于诊断不足而缺乏数据。肝静脉综合征由下腔静脉(IVC)肝段反复发生的细菌性血栓性静脉炎引起,导致内膜增厚和阻塞,最终引发肝硬化和肝细胞癌等并发症。

病例介绍

一名32岁的阿富汗难民女性,出现进行性腹部膨隆。初步检查显示贫血、脾肿大和大量腹水。进一步检查发现肝硬化、静脉曲张和下腔静脉狭窄段。她被诊断为肝静脉综合征,接受了下腔静脉支架置入术,并开始服用氯吡格雷和达比加群。结论肝静脉综合征常被误诊,需要高度怀疑,对于社会经济背景较低的肝硬化患者应予以考虑。早期诊断可预防肝硬化和肝细胞癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e47c/12118078/f203b1cd0b62/omaf035f1.jpg

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