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含番泻苷的不同饮食方案用于结肠镜检查前肠道清洁的比较:一项随机对照试验

Comparison of Various Diet Regimens Involving Sennoside for Bowel Cleansing Prior to Colonoscopy: A Randomized Controlled Trial.

作者信息

Bozkurt Hilmi, Reyhan Enver, Özcan Cumhur, Çolak Tahsin, Beştaş Mustafa Onur, Yıldırım Didem Derici

机构信息

Department of General Surgery, Faculty of Medicine, Mersin University.

Department of Biostatistics and Medical Informatics,. Mersin, Turkey Mersin University, Mersin, Turkey.

出版信息

Surg Laparosc Endosc Percutan Tech. 2025 Aug 1;35(4):e1368. doi: 10.1097/SLE.0000000000001368.

DOI:10.1097/SLE.0000000000001368
PMID:40444380
Abstract

BACKGROUND

Consuming only low-fiber food on the day before the procedure is recommended as standard practice for bowel cleansing in patients using polyethylene glycol (PEG). However, there have been few studies to date investigating the optimal dietary regimen for patients using the more cost-effective Sennoside A+B calcium before colonoscopy. The present study compares the quality of bowel preparation of patients following a clear diet and those following a low-fiber diet on the day before colonoscopy among patients using Sennoside A+B calcium.

METHODS

This prospective, randomized, and investigator-blinded study was conducted between November 2023 and February 2024. Included in the study were 150 patients aged 18 years and over with a mean age of 55.6±14 years, with 75 patients assigned to the clear diet group and 75 patients to the low-fiber diet group. The assessment of colonoscopy cleanliness before colonoscopy was conducted using the Boston Bowel Preparation Scale (BBPS).

RESULTS

None of the patients experienced intolerance. The mean overall total cleanliness score, measured using the BBPS, was 7.24±2.1, with 7.48 ± 2.1 in the low-fiber diet group and 7.0 ±2.1 in the clear liquid diet group. No significant difference in cleanliness was found between the 2 groups ( P =0.096).

CONCLUSION

Patients using cost-effective Senna for bowel cleansing before colonoscopy can safely consume low-fiber foods on the day before the procedure. In the present study, a clear diet offered no benefit over a more comfortable and better-tolerated diet in terms of colon cleanliness.

摘要

背景

对于使用聚乙二醇(PEG)进行肠道准备的患者,术前一天仅食用低纤维食物是推荐的标准做法。然而,迄今为止,很少有研究调查在结肠镜检查前使用更具成本效益的番泻苷A+B钙的患者的最佳饮食方案。本研究比较了使用番泻苷A+B钙的患者在结肠镜检查前一天遵循清流食饮食和低纤维饮食的肠道准备质量。

方法

本前瞻性、随机、研究者盲法研究于2023年11月至2024年2月进行。纳入研究的是150名年龄在18岁及以上的患者,平均年龄为55.6±14岁,其中75名患者被分配到清流食饮食组,75名患者被分配到低纤维饮食组。结肠镜检查前使用波士顿肠道准备量表(BBPS)对结肠镜检查清洁度进行评估。

结果

所有患者均未出现不耐受情况。使用BBPS测量的平均总体清洁度评分为7.24±2.1,低纤维饮食组为7.48±2.1,清流食饮食组为7.0±2.1。两组之间的清洁度没有显著差异(P = 0.096)。

结论

在结肠镜检查前使用具有成本效益的番泻叶进行肠道准备的患者在术前一天可以安全地食用低纤维食物。在本研究中,就结肠清洁度而言,清流食饮食相较于更舒适且耐受性更好的饮食并无优势。

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