成人发生的神经上皮瘤（神经母细胞瘤）。病例报告。
Neuroepithelioma (neuroblastoma) arising in an adult. A case report.
作者信息
Verwey J, Slater R, Kamphorst W, Pinedo H M
出版信息
J Cancer Res Clin Oncol. 1985;110(2):165-9. doi: 10.1007/BF00402733.
Abstract
Cytogenetic studies on neuroblastomas arising in children have revealed consistent abnormalities of the short arm of chromosome number 1. Partly because of the rare occurrence of neuroblastomas in adults, extensive cytogenetic studies in this group of patients have not been performed. We report a case of a neuroepithelioma (neuroblastoma) arising in a 50-year-old male patient. On chromosome analysis of a metastasis, a stemline with karyotype 47,XY, +der1 (1 qter---1 cen::1q21---1 qter) was identified. The possible consequences of this result and those of results previously reported in the literature are discussed.
摘要
对儿童神经母细胞瘤进行的细胞遗传学研究显示，1号染色体短臂存在一致性异常。部分由于神经母细胞瘤在成人中罕见，尚未对该组患者进行广泛的细胞遗传学研究。我们报告一例发生于一名50岁男性患者的神经上皮瘤（神经母细胞瘤）。在对一个转移灶进行染色体分析时，鉴定出一个核型为47,XY, +der1 (1 qter---1 cen::1q21---1 qter)的干系。本文讨论了该结果以及先前文献报道结果可能产生的后果。
相似文献
1
Neuroepithelioma (neuroblastoma) arising in an adult. A case report.成人发生的神经上皮瘤（神经母细胞瘤）。病例报告。
J Cancer Res Clin Oncol. 1985;110(2):165-9. doi: 10.1007/BF00402733.
2
123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma.用于诊断神经母细胞瘤的123I-间碘苄胍闪烁扫描术和18F-氟代脱氧葡萄糖正电子发射断层显像
Cochrane Database Syst Rev. 2015 Sep 29;2015(9):CD009263. doi: 10.1002/14651858.CD009263.pub2.
3
Retinoic acid postconsolidation therapy for high-risk neuroblastoma patients treated with autologous haematopoietic stem cell transplantation.维甲酸巩固治疗用于接受自体造血干细胞移植的高危神经母细胞瘤患者。
Cochrane Database Syst Rev. 2017 Aug 25;8(8):CD010685. doi: 10.1002/14651858.CD010685.pub3.
4
Retinoic acid post consolidation therapy for high-risk neuroblastoma patients treated with autologous hematopoietic stem cell transplantation.维甲酸巩固治疗用于接受自体造血干细胞移植的高危神经母细胞瘤患者。
Cochrane Database Syst Rev. 2015 Jan 29;1:CD010685. doi: 10.1002/14651858.CD010685.pub2.
5
High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma.大剂量化疗及自体造血干细胞救援用于高危神经母细胞瘤患儿
Cochrane Database Syst Rev. 2015 Oct 5;2015(10):CD006301. doi: 10.1002/14651858.CD006301.pub4.
6
Rapid COJEC versus standard induction therapies for high-risk neuroblastoma.用于高危神经母细胞瘤的快速COJEC与标准诱导疗法对比
Cochrane Database Syst Rev. 2015 May 19;2015(5):CD010774. doi: 10.1002/14651858.CD010774.pub2.
7
High-dose chemotherapy and autologous haematopoietic stem cell rescue for children with high-risk neuroblastoma.大剂量化疗及自体造血干细胞救援用于高危神经母细胞瘤患儿
Cochrane Database Syst Rev. 2013 Aug 22(8):CD006301. doi: 10.1002/14651858.CD006301.pub3.
8
The Black Book of Psychotropic Dosing and Monitoring.《精神药物剂量与监测黑皮书》
Psychopharmacol Bull. 2024 Jul 8;54(3):8-59.
9
Vaccines for preventing influenza in the elderly.用于预防老年人流感的疫苗。
Cochrane Database Syst Rev. 2018 Feb 1;2(2):CD004876. doi: 10.1002/14651858.CD004876.pub4.
10
Can a Liquid Biopsy Detect Circulating Tumor DNA With Low-passage Whole-genome Sequencing in Patients With a Sarcoma? A Pilot Evaluation.液体活检能否通过低深度全基因组测序检测肉瘤患者的循环肿瘤DNA？一项初步评估。
Clin Orthop Relat Res. 2025 Jan 1;483(1):39-48. doi: 10.1097/CORR.0000000000003161. Epub 2024 Jun 21.
本文引用的文献
1
Maturation of sympathicoblastoma into ganglioneuroma; report of 2 patients with 20-and 46-year survivals respectively.交感神经母细胞瘤向神经节神经瘤的成熟；分别报告2例存活20年和46年的患者。
Cancer. 1959 Jan-Feb;12(1):108-16. doi: 10.1002/1097-0142(195901/02)12:1<108::aid-cncr2820120116>3.0.co;2-h.
2
Peripheral neuroepithelioma: a light and electron microscopic study.外周神经上皮瘤：光镜和电镜研究
Cancer. 1980 Dec 1;46(11):2456-62. doi: 10.1002/1097-0142(19801201)46:11<2456::aid-cncr2820461126>3.0.co;2-v.
3
Break points in chromosome #1 abnormalities of 218 human neoplasms.218例人类肿瘤1号染色体异常的断点
Cancer Genet Cytogenet. 1981 Nov;4(3):215-25. doi: 10.1016/0165-4608(81)90015-7.
4
Treatment of adult neuroblastoma.成人神经母细胞瘤的治疗。
Cancer. 1980 Mar 1;45(5):840-4. doi: 10.1002/1097-0142(19800301)45:5<840::aid-cncr2820450503>3.0.co;2-z.
5
Chromosome analysis of a human neuroblastoma.人类神经母细胞瘤的染色体分析
Cancer Res. 1981 Aug;41(8):2995-9.
6
Abnormalities of chromosome 1p in human neuroblastoma tumors and cell lines.人类神经母细胞瘤肿瘤及细胞系中1号染色体短臂的异常。
Cancer Genet Cytogenet. 1982 Sep;7(1):33-42. doi: 10.1016/0165-4608(82)90105-4.
7
Malignant neuroepithelioma (peripheral neuroblastoma). A clinicopathologic study of 15 cases.恶性神经上皮瘤（外周神经母细胞瘤）。15例临床病理研究。
Am J Surg Pathol. 1983 Jun;7(4):309-18. doi: 10.1097/00000478-198306000-00002.
8
Chromosome analysis of human neuroblastoma cell line TR14 showing double minutes and an aberration involving chromosome 1.人神经母细胞瘤细胞系TR14的染色体分析显示双微体和涉及1号染色体的畸变。
Cancer Genet Cytogenet. 1983 Jul;9(3):273-80. doi: 10.1016/0165-4608(83)90011-0.
9
Mapping of the human Blym-1 transforming gene activated in Burkitt lymphomas to chromosome 1.在伯基特淋巴瘤中激活的人类Blym-1转化基因定位于1号染色体。
Science. 1984 Jan 13;223(4632):173-5. doi: 10.1126/science.6691143.
10
The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1.神经生长因子β亚基的人类基因位于1号染色体短臂近端。
Science. 1983 Dec 16;222(4629):1248-51. doi: 10.1126/science.6648531.
Zotero 插件