Campbell M J, Elwood P C, Mackean J, Waters W E
J Chronic Dis. 1985;38(10):881-9. doi: 10.1016/0021-9681(85)90113-4.
The mortality of 1438 women aged 45-74 from South Wales has been studied from 1967-1978 using techniques of survival analysis to determine whether the haemoglobin level (Hb) or the haematocrit (PCV) are risk factors for death due to ischaemic heart disease (IHD), cerebrovascular accident (CVA) or cancer. In the 858 women who were not menstruating and who did not complain of angina at the time of the survey a PCV over 45% was a significant risk factor for IHD mortality. An Hb level over 14 g/dl was also a risk factor but this failed to reach conventional significance, when smoking was allowed for. In the 1098 women who were not menstruating an Hb less than 12 g/dl or a PCV less than 40% are increased risk factors for cancer and this risk persisted throughout the follow-up period. Neither Hb nor PCV were significant risk factors for CVA mortality.
1967年至1978年期间，运用生存分析技术对1438名年龄在45至74岁之间的南威尔士女性的死亡率进行了研究，以确定血红蛋白水平（Hb）或血细胞比容（PCV）是否为缺血性心脏病（IHD）、脑血管意外（CVA）或癌症所致死亡的风险因素。在调查时未处于月经期且未主诉心绞痛的858名女性中，PCV超过45%是IHD死亡率的一个显著风险因素。Hb水平超过14 g/dl也是一个风险因素，但在考虑吸烟因素后，该因素未达到传统意义上的显著性。在1098名未处于月经期的女性中，Hb低于12 g/dl或PCV低于40%是癌症的风险增加因素，且这种风险在整个随访期内持续存在。Hb和PCV均不是CVA死亡率的显著风险因素。
