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坦桑尼亚2022年人口与住房普查结果对坦桑尼亚老年人神经心理测试的开发与适用性的临床及研究意义。

Clinical and research implications of the findings of the Tanzania 2022 Population and Housing Census for the development and suitability of neuropsychological tests for older adults in Tanzania.

作者信息

Mlaki Damas Andrea, Valcour Victor, Milicic Andjelika, Allen Elaine, Paddick Stella-Maria, Berkowitz Aaron, Kiama Raina, Miller Bruce

机构信息

Global Brain Health Institute, University of California San Francisco, Suite 3C08, Weill Neurosciences, 1651 4th Street, Box 3020, San Francisco, CA, 94143, USA.

Directorate of Medical Services, Mirembe National Mental Health Hospital, Hazina, Dodoma, 41108, Tanzania.

出版信息

BMC Geriatr. 2025 May 30;25(1):392. doi: 10.1186/s12877-025-06071-9.

Abstract

BACKGROUND

The identification of dementia using valid and reliable neuropsychological tests is crucial for the development of effective preventive interventions, treatments, and care plans.

METHODS

We analysed the 2022 Population and Housing Census data in Tanzania to determine the age-adjusted prevalence of subjective memory, hearing, and visual complaints and explore factors that may influence the development and suitability of neuropsychological assessment batteries among adults aged 60 and older. Age-adjusted prevalence estimates were calculated using the WHO Direct Method. Logistic regression models were performed to examine the factors associated with memory complaints. Mediation analysis was conducted using path analysis, and the significance of the indirect effects was tested using bootstrapping procedures.

RESULTS

Adults aged 60 + constituted 5.7% of the population. The median (IQR) age was 68 (60-97) years. Literacy and numeracy rates were 59.7% and 67.7% respectively. The age-adjusted prevalence of subjective memory, hearing, and visual complaints, were 7.3% (95%CI: 7.2-7.4), 7.5% (95%CI: 7.4-7.6), and 16.3% (95%CI: 16.2- 16.4). Being married (AOR 0.83; 95%CI: 0.74-0.93; p = 0.002) and having a seven-year education or more (p ≤ 0.001) reduced the odds of memory complaints, while hearing (AOR = 4.62; 95%CI: 4.37-4.88; p ≤ 0.001) and visual (AOR 7.12; 95%CI: 6.78-7.47; p ≤ 0.001) complaints increased the likelihood of memory complaints. Age (p ≤ 0.001) and female sex (p ≤ 0.001) accounted for 21% and 7% of the effects of sex and education on subjective memory complaints respectively.

CONCLUSION

Literacy and numeracy decrease with age in adults aged 60 and older in Tanzania. Hearing and visual complaints are common among seniors; they are more prevalent in rural areas and increase the risk of memory complaints. Our findings may inform the development and suitability of neuropsychological tests for seniors and highlight the need for policymakers to develop dementia prevention interventions and improve access to vision and hearing services for this group.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

使用有效且可靠的神经心理学测试来识别痴呆症对于制定有效的预防干预措施、治疗方法和护理计划至关重要。

方法

我们分析了坦桑尼亚2022年人口与住房普查数据,以确定主观记忆、听力和视觉问题的年龄调整患病率,并探索可能影响60岁及以上成年人神经心理学评估量表的发展和适用性的因素。年龄调整患病率估计值采用世界卫生组织直接法计算。进行逻辑回归模型以检查与记忆问题相关的因素。使用路径分析进行中介分析,并使用自抽样程序检验间接效应的显著性。

结果

60岁及以上成年人占人口的5.7%。年龄中位数(四分位距)为68岁(60 - 97岁)。识字率和算术率分别为59.7%和67.7%。主观记忆、听力和视觉问题的年龄调整患病率分别为7.3%(95%置信区间:7.2 - 7.4)、7.5%(95%置信区间:7.4 - 7.6)和16.3%(95%置信区间:16.2 - 16.4)。已婚(调整后比值比0.83;95%置信区间:0.74 - 0.93;p = 0.002)和接受过七年或以上教育(p≤0.001)可降低记忆问题的几率,而听力问题(调整后比值比 = 4.62;95%置信区间:4.37 - 4.88;p≤0.001)和视觉问题(调整后比值比7.12;

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15d0/12123829/1744db0b921c/12877_2025_6071_Fig1_HTML.jpg

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