Lee Young Jin, Kwon Eun Ja, Park Da-In, Park Sang Hyoung, Hwang Sung Wook, Ye Byong Duk
College of Nursing, Eulji University, 712, Dongil-ro, Uijeongbu, Gyeonggi-do, 117759, Republic of Korea.
Department of Nursing and Inflammatory Bowel Disease Center, Asan Medical Center, 88, Olympic-ro 43-gil, Sonpa-gu, Seoul, 05505, Republic of Korea.
BMC Gastroenterol. 2025 May 30;25(1):417. doi: 10.1186/s12876-025-03962-4.
Obesity in patients with inflammatory bowel disease (IBD) not only exacerbates symptoms but also interferes with treatment and leads to additional complications. Therefore, managing weight loss and preventing obesity are crucial. This study was designed to develop and implement a 10-week walking exercise program, facilitated by a mobile application, to evaluate its effectiveness in managing weight in obese IBD patients.
This study was designed as a single-blind parallel-group randomized clinical trial. We enrolled 54 participants, randomly allocating 27 to the intervention group and 27 to the control group. The intervention group received educational materials, such as videos, and participants were instructed to walk a minimum of 7,000 steps on at least five days each week for a duration of 10 weeks. Additionally, they were required to submit weekly updates on weight-related information to the researchers. The primary outcomes measured were body mass index (BMI), body fat percentage, and skeletal muscle mass. Secondary outcomes included perceived stress, fatigue, and quality of life.
A total of 49 participants were included in the data collection (intervention group: n = 24, control group: n = 25). Post-intervention, the intervention group demonstrated significant reductions in BMI (t = 3.57, p =.001) and body fat percentage (Z = 3.11, p =.002) compared to the control group. Furthermore, perceived stress (t = 2.20, p =.038) and fatigue (t = 2.10, p =.047) significantly decreased in the intervention group, but no significant differences were observed when compared to the control group.
The 10-week walking program utilizing a mobile app effectively reduced body fat among participants, indicating its potential to improve health management in clinical settings. Further research is necessary to explore changes in muscle mass and psychological variables.
Korea Clinical Trials Registry number KCT0009461, 24/05/2024.
炎症性肠病（IBD）患者的肥胖不仅会加重症状，还会干扰治疗并导致其他并发症。因此，控制体重减轻和预防肥胖至关重要。本研究旨在开发并实施一项为期10周的步行锻炼计划，该计划由一款移动应用程序辅助，以评估其对肥胖IBD患者体重管理的有效性。
本研究设计为单盲平行组随机临床试验。我们招募了54名参与者，随机将27名分配到干预组，27名分配到对照组。干预组收到了视频等教育材料，并被指示每周至少五天每天步行至少7000步，持续10周。此外，他们被要求每周向研究人员提交与体重相关信息的更新。测量的主要结果是体重指数（BMI）、体脂百分比和骨骼肌质量。次要结果包括感知压力、疲劳和生活质量。
共有49名参与者纳入数据收集（干预组：n = 24，对照组：n = 25）。干预后，与对照组相比，干预组的BMI（t = 3.57，p = .001）和体脂百分比（Z = 3.11，p = .002）显著降低。此外，干预组的感知压力（t = 2.20，p = .038）和疲劳（t = 2.10，p = .047）显著降低，但与对照组相比未观察到显著差异。
利用移动应用程序的10周步行计划有效降低了参与者的体脂，表明其在临床环境中改善健康管理的潜力。有必要进一步研究以探索肌肉质量和心理变量的变化。
韩国临床试验注册号KCT0009461，2024年5月24日。
