Marques Lucas Murrins, Strauss Allan, Castellani Ana, Barbosa Sara, Simis Marcel, Fregni Felipe, Battistella Linamara
Mental Health Department, Santa Casa de São Paulo School of Medical Sciences, Dona Veridiana Street 55, 3o. Floor, Higienópolis, São Paulo, SP, Brazil.
Instituto de Medicina Física e Reabilitação, Faculdade de Medicina, Hospital das Clínicas HCFMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.
Exp Brain Res. 2025 May 31;243(7):160. doi: 10.1007/s00221-025-07116-6.
Event-related desynchronization (ERD) and event-related synchronization (ERS) are critical neurophysiological phenomena associated with motor execution and inhibitory processes. Their utility spans neurophysiological biomarker research and Brain-Computer Interface (BCI) development. However, standardized frameworks for analyzing ERD and ERS oscillations across motor tasks and frequency ranges remain scarce. This study conducted a cross-sectional analysis of 76 healthy participants from the DEFINE cohort to explore ERD and ERS variations across four motor-related tasks (Motor Execution, Motor Imagery, Active Observation, and Passive Observation) and six frequency bands (Delta, Theta, Low Alpha, High Alpha, Low Beta, and High Beta) using C3 electrode activity. Repeated measures ANOVA revealed task-sensitive ERD and ERS power modulations, with oscillatory responses spanning the 1-30 Hz spectrum. Beta activity exhibited pronounced differences between tasks, highlighting its relevance in motor control, while other bands showed distinct task-dependent variations. These findings underscore the variability in ERD/ERS patterns across different tasks and frequency bands, reinforcing the importance of further research into standardized analytical frameworks. By refining ERD/ERS analyses, our study contributes to developing reference frameworks that can enhance clinical and Brain-Computer Interface (BCI) applications.
事件相关去同步化（ERD）和事件相关同步化（ERS）是与运动执行和抑制过程相关的关键神经生理现象。它们的应用涵盖神经生理生物标志物研究和脑机接口（BCI）开发。然而，用于分析跨运动任务和频率范围的ERD和ERS振荡的标准化框架仍然稀缺。本研究对DEFINE队列中的76名健康参与者进行了横断面分析，以使用C3电极活动探索四个与运动相关的任务（运动执行、运动想象、主动观察和被动观察）和六个频段（δ波、θ波、低α波、高α波、低β波和高β波）中的ERD和ERS变化。重复测量方差分析揭示了任务敏感的ERD和ERS功率调制，振荡响应范围为1 - 30赫兹频谱。β波活动在任务之间表现出明显差异，突出了其在运动控制中的相关性，而其他频段则表现出明显的任务依赖性变化。这些发现强调了不同任务和频段中ERD/ERS模式的变异性，强化了进一步研究标准化分析框架的重要性。通过完善ERD/ERS分析，我们的研究有助于开发可增强临床和脑机接口（BCI）应用的参考框架。
