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小儿经皮肾镜取石术后长期尿漏的危险因素:碎石技术的比较研究

Risk factors for prolonged urine leakage following pediatric percutaneous nephrolithotomy: A comparative study of lithotripsy techniques.

作者信息

Akdogan Nebil, Arikan Mehmet Gurkan, Yilmaz Ismail Onder, Ates Tunahan, Deger Mutlu, Satar Nihat, Arıdogan Ibrahim Atilla

机构信息

Faculty of Medicine, Department of Urology, Cukurova University, Adana, Turkey.

Department of Urology, Defne State Hospital, Hatay, Turkey.

出版信息

World J Urol. 2025 May 31;43(1):345. doi: 10.1007/s00345-025-05710-5.

DOI:10.1007/s00345-025-05710-5
PMID:40450057
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12126308/
Abstract

OBJECTIVE

This study aimed to identify the risk factors associated with prolonged urine leakage (PUL) following pediatric percutaneous nephrolithotomy (PCNL) with a specific focus on the impact of lithotripter type.

METHODS

Data from 847 pediatric PCNL patients treated between August 1997 and February 2024 were collected. Patients were categorized into two groups based on the urine leakage time: prolonged leakage (> 24 h) and normal leakage. Logistic regression analysis was used to identify determinants of prolonged urine leakage.

RESULTS

The study found that the use of laser lithotripters (LL) significantly increased the risk of prolonged urine leakage compared with pneumatic lithotripters (PL) (OR, 3.1; 95% CI: 1.68-5.76, p < 0.001). Additionally, larger access diameters (≥ 26 Fr), larger stone sizes (> 350 cc), and younger age (< 6 years) were associated with an increased risk of PUL. Patients who underwent procedures with multiple accesses were also at a higher risk of PUL. Despite this, conservative management without the use of DJ stents is effective in most cases.

CONCLUSION

The use of PL in pediatric cases is associated with a lower risk of PUL than LL. Factors such as the access diameter, stone size, and patient age can predict the likelihood of PUL. Conservative management is recommended in most patients to avoid increased morbidity.

摘要

目的

本研究旨在确定小儿经皮肾镜取石术(PCNL)后长期漏尿(PUL)的相关危险因素,特别关注碎石机类型的影响。

方法

收集了1997年8月至2024年2月期间接受治疗的847例小儿PCNL患者的数据。根据漏尿时间将患者分为两组:长期漏尿(>24小时)和正常漏尿。采用逻辑回归分析确定长期漏尿的决定因素。

结果

研究发现,与气压弹道碎石机(PL)相比,使用激光碎石机(LL)显著增加了长期漏尿的风险(OR,3.1;95%CI:1.68 - 5.76,p < 0.001)。此外,较大的通道直径(≥26F)、较大的结石体积(>350cc)和较年轻的年龄(<6岁)与PUL风险增加相关。接受多次通道手术的患者发生PUL的风险也更高。尽管如此,在大多数情况下,不使用DJ支架的保守治疗是有效的。

结论

小儿病例中使用PL与PUL风险低于LL相关。通道直径、结石大小和患者年龄等因素可预测PUL的可能性。建议大多数患者采用保守治疗以避免发病率增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb18/12126308/e1f897fe7e27/345_2025_5710_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb18/12126308/8eeaffb1c479/345_2025_5710_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb18/12126308/e1f897fe7e27/345_2025_5710_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb18/12126308/8eeaffb1c479/345_2025_5710_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb18/12126308/e1f897fe7e27/345_2025_5710_Fig2_HTML.jpg

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本文引用的文献

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Am J Clin Exp Urol. 2023 Jun 15;11(3):258-264. eCollection 2023.
2
Optimization of the outcome of percutaneous nephrolithotomy regarding urinary leakage, what should we do?经皮肾镜取石术术后尿外渗的优化处理,我们应该怎么做?
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The feasibility of one-day length of hospital stay after pediatric percutaneous nephrolithotomy.
小儿经皮肾镜取石术后住院 1 天的可行性。
Urologia. 2022 Feb;89(1):126-130. doi: 10.1177/0391560321993594. Epub 2021 Feb 7.
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Comparison of Effect of Minimally Invasive Percutaneous Nephrolithotomy on Split Renal Function: Single Tract vs Multiple Tracts.微创经皮肾镜取石术对分肾功能影响的比较:单通道与多通道
J Endourol. 2017 Apr;31(4):361-365. doi: 10.1089/end.2016.0822. Epub 2017 Feb 3.
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Study of predictive factors affecting the prolonged urinary leakage after percutaneous nephrolithotomy.经皮肾镜取石术后影响长期尿漏的预测因素研究
Urol Ann. 2016 Jan-Mar;8(1):60-5. doi: 10.4103/0974-7796.164856.
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Comparison of efficacy of laser lithotripter with ultrasonic lithotripter in mini percutaneous nephrolithotomy.
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Incidence, prevention, and management of complications following percutaneous nephrolitholapaxy.经皮肾镜碎石取石术后并发症的发生率、预防和处理。
Eur Urol. 2012 Jan;61(1):146-58. doi: 10.1016/j.eururo.2011.09.016. Epub 2011 Sep 28.
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Modified Clavien classification in percutaneous nephrolithotomy: assessment of complications in children.经皮肾镜取石术改良 Clavien 分级:评估儿童并发症。
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