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中国汉族患者门诊前路颈椎间盘切除融合术的初步临床研究:一项回顾性分析

Preliminary clinical study of outpatient anterior cervical discectomy and fusion in Chinese Han patients: a retrospective analysis.

作者信息

Luo Lun, Chen Zhizhong, Dai Jun, Zhao Xushen, Zhou Zhentao, Zhang Min, Zhou Xiaozhong

机构信息

Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Department of Orthopaedics, Sichuan Science City Hospital, Mianyang, China.

出版信息

Asian Spine J. 2025 Aug;19(4):561-570. doi: 10.31616/asj.2024.0341. Epub 2025 May 30.

DOI:10.31616/asj.2024.0341
PMID:40451619
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12400091/
Abstract

STUDY DESIGN

A retrospective analysis.

PURPOSE

To investigate the safety, clinical efficacy, and health economic benefits of anterior cervical discectomy and fusion (ACDF) among Chinese Han patients in an outpatient setting.

OVERVIEW OF LITERATURE

For years, ACDF has been conducted in an outpatient setting in Western countries. However, studies addressing whether this type of surgery carries the same level of safety and clinical efficacy for Chinese Han patients are scarce.

METHODS

A retrospective analysis was conducted based on the clinical data of Han patients who underwent ACDF between January 2022 and May 2024. A total of 84 patients were included, and 1:1 propensity score matching was employed between 42 patients who underwent outpatient ACDF and 42 who underwent inpatient ACDF before evaluating the safety and clinical efficacy.

RESULTS

The mean follow-up period was 3.9 months (range, 1-12 months). The fibrinogen and activated partial thromboplastin time of the outpatient and inpatient groups were comparable, which were different from the data of Caucasians in the literature. No significant differences in adverse events within 30 days following the surgery were found between the outpatient (28.6%) and inpatient (33.3%) groups. No significant differences in the Japanese Orthopaedic Association score and Neck Disability Index were noted between the two groups 1 month before and after the surgery. The readmission rates were low in the outpatient group 30 days after surgery (2.4%).

CONCLUSIONS

Consistent with the Caucasian and Black, one- to two-level ACDF conducted on Chinese Han patients in an outpatient setting demonstrated comparable safety and clinical effectiveness to routine inpatient settings.

摘要

研究设计

回顾性分析。

目的

探讨门诊环境下中国汉族患者前路颈椎间盘切除融合术(ACDF)的安全性、临床疗效和健康经济效益。

文献综述

多年来,西方国家一直在门诊环境中开展ACDF手术。然而,针对这类手术对中国汉族患者是否具有相同水平的安全性和临床疗效的研究却很少。

方法

基于2022年1月至2024年5月期间接受ACDF手术的汉族患者的临床数据进行回顾性分析。共纳入84例患者,在评估安全性和临床疗效之前,对42例行门诊ACDF手术的患者和42例行住院ACDF手术的患者进行1:1倾向评分匹配。

结果

平均随访期为3.9个月(范围1 - 12个月)。门诊组和住院组的纤维蛋白原及活化部分凝血活酶时间相当,这与文献中白种人的数据不同。门诊组(28.6%)和住院组(33.3%)术后30天内不良事件无显著差异。两组手术前后1个月的日本骨科协会评分和颈部功能障碍指数无显著差异。门诊组术后30天再入院率较低(2.4%)。

结论

与白种人和黑人一致,门诊环境下对中国汉族患者进行的一至二级ACDF手术与常规住院环境相比,安全性和临床有效性相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a0/12400091/c2ddf2028b5e/asj-2024-0341f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a0/12400091/c2ddf2028b5e/asj-2024-0341f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9a0/12400091/c2ddf2028b5e/asj-2024-0341f1.jpg

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