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胆囊切除术后胆囊管残端胆漏的内镜治疗:单中心经验

Endoscopic management of post-cholecystectomy cystic duct stump biliary leakage: Single-centre experience.

作者信息

Ciesielski Wojciech, Klimczak Tomasz, Durczyński Adam, Strzelczyk Janusz, Hogendorf Piotr

机构信息

Department of General and Transplant Surgery, Medical University of Lodz, Lodz, Poland.

出版信息

Turk J Surg. 2025 May 30;41(2):193-197. doi: 10.47717/turkjsurg.2025.6616.

DOI:10.47717/turkjsurg.2025.6616
PMID:40452207
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12124330/
Abstract

OBJECTIVE

Biliary leakage from the cystic duct stump following cholecystectomy is a significant postoperative complication. Endoscopic retrograde cholangiopancreatography (ERCP) with stenting has become the preferred treatment due to its minimally invasive nature and high success rates.

MATERIAL AND METHODS

This study retrospectively evaluates the efficacy of ERCP for managing cystic duct stump leakage. A total of 29 patients treated between February 2017 and April 2024 were analyzed. Inclusion criteria included patients with confirmed cystic duct leakage. Primary and secondary success rates were defined as bile leakage cessation and absence of biliary fistula after stent removal, respectively.

RESULTS

The group consisted of 20 females and 9 males, with an average age of 64.14 years and median body mass index of 27.7 kg/m². Cholelithiasis without acute cholecystitis was the primary surgical indication in 48% of cases. ERCP was the first-choice treatment for 89.7% of patients, using stents based on common bile duct width. Initial success was achieved in 89.7% of cases, with a mean drain removal time of 14.3 days. Secondary success was seen in 96.4% of patients. Complications, such as pancreatitis and stent migration, occurred in 13.8% of cases.

CONCLUSION

The study highlights the effectiveness of ERCP in managing cystic duct leaks, with high success and acceptable complication rates, confirming it should be the treatment of choice for this condition.

摘要

目的

胆囊切除术后胆囊管残端胆漏是一种严重的术后并发症。内镜逆行胰胆管造影术(ERCP)联合支架置入术因其微创性和高成功率已成为首选治疗方法。

材料与方法

本研究回顾性评估ERCP治疗胆囊管残端漏的疗效。分析了2017年2月至2024年4月期间接受治疗的29例患者。纳入标准包括确诊为胆囊管漏的患者。主要成功率和次要成功率分别定义为胆汁漏停止和支架取出后无胆瘘。

结果

该组包括20名女性和9名男性,平均年龄64.14岁,中位体重指数为27.7kg/m²。48%的病例中,无急性胆囊炎的胆结石是主要手术指征。89.7%的患者将ERCP作为首选治疗方法,根据胆总管宽度使用支架。89.7%的病例取得了初步成功,平均引流管拔除时间为14.3天。96.4%的患者取得了次要成功。13.8%的病例发生了胰腺炎和支架移位等并发症。

结论

该研究强调了ERCP治疗胆囊管漏的有效性,成功率高且并发症发生率可接受,证实其应为这种情况的首选治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/12124330/d51c56a3f06b/TurkJSurg-41-2-193-figure-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/12124330/45506b8dd417/TurkJSurg-41-2-193-figure-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/12124330/e36ed7b3f1fe/TurkJSurg-41-2-193-figure-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/12124330/d51c56a3f06b/TurkJSurg-41-2-193-figure-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/12124330/45506b8dd417/TurkJSurg-41-2-193-figure-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/12124330/e36ed7b3f1fe/TurkJSurg-41-2-193-figure-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c392/12124330/d51c56a3f06b/TurkJSurg-41-2-193-figure-3.jpg

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本文引用的文献

1
Management of Bile Leak Post Minimally Invasive Subtotal Cholecystectomy: A Review.微创次全胆囊切除术后胆漏的管理:综述
Ann Surg. 2025 Apr 29. doi: 10.1097/SLA.0000000000006744.
2
Comparative Effectiveness of Different Cystic Duct Ligation Techniques in Laparoscopic Cholecystectomy: A Systematic Review and Network Meta-Analysis.腹腔镜胆囊切除术中不同胆囊管结扎技术的比较效果:一项系统评价与网状Meta分析
J Laparoendosc Adv Surg Tech A. 2025 Jan;35(1):31-35. doi: 10.1089/lap.2024.0295. Epub 2024 Nov 28.
3
Spontaneous Closure of Bile Leak in Abdominal Drain after Cholecystectomy: A Systematic Review.
胆囊切除术后腹腔引流胆汁漏的自然闭合:系统评价。
J Coll Physicians Surg Pak. 2024 Sep;34(9):1084-1089. doi: 10.29271/jcpsp.2024.09.1084.
4
Post-operative complications of cholecystectomy: what the radiologist needs to know.胆囊切除术后并发症:放射科医生需要了解的内容。
Abdom Radiol (NY). 2025 Jan;50(1):109-130. doi: 10.1007/s00261-024-04387-5. Epub 2024 Jun 28.
5
Usefulness of Intraductal Placement of a Dumbbell-Shaped Fully Covered Self-Expandable Metal Stent for Post-Cholecystectomy Bile Leaks.哑铃形全覆膜自膨式金属支架胆管内放置在胆囊切除术后胆漏治疗中的应用价值
J Clin Med. 2023 Oct 14;12(20):6530. doi: 10.3390/jcm12206530.
6
Efficacy and associated factors of endoscopic transpapillary drainage for postoperative biliary leakage.内镜下经乳头引流术治疗术后胆漏的疗效及相关因素
DEN Open. 2023 Aug 17;4(1):e281. doi: 10.1002/deo2.281. eCollection 2024 Apr.
7
Do not get stumped: multimodality imaging findings of early and late post-cholecystectomy complications.别被难住了:胆囊切除术后早晚期并发症的多模态影像学表现。
Emerg Radiol. 2023 Jun;30(3):351-362. doi: 10.1007/s10140-023-02131-y. Epub 2023 Apr 12.
8
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Emerg Med Int. 2022 May 14;2022:6555150. doi: 10.1155/2022/6555150. eCollection 2022.
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