Pizzorno Joseph
Integr Med (Encinitas). 2025 Jun;24(3):6-8.
Animal and human biochemistry and physiology developed over millennia under widely varying environments and available sources of nutrition. The genome evolved to optimize survival and reproduction in surprisingly diverse ways. A clinically important aspect of this evolution is that SNP manifestations changed to match the variants in food molecules required for life such as vitamins. This editorial discusses the interaction between SNPs and vitamers, the varied forms in which vitamins occur.
动物和人类的生物化学与生理学在数千年的时间里,在广泛多样的环境和可得的营养来源下发展起来。基因组以惊人多样的方式进化以优化生存和繁殖。这种进化在临床上的一个重要方面是,单核苷酸多态性(SNP)的表现发生了变化,以匹配生命所需食物分子(如维生素)中的变体。这篇社论讨论了SNP与维生素异构体(维生素存在的多种形式)之间的相互作用。