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1例乳腺浸润性小叶癌伴胃和子宫转移经F-18 FDG PET CT证实

A Case of Invasive Lobular Carcinoma of the Breast Presenting with Gastric and Uterine Metastases Demonstrated on F-18 FDG PET CT.

作者信息

Kulkarni Pramukh, Shankaramurthy Gayana, Belathur Vivek, Ravindra B S

机构信息

Department of Nuclear Medicine and PET CT, Fortis Hospital, Bengaluru, Karnataka, India.

Department of Medical Oncology, Fortis Hospital, Bengaluru, Karnataka, India.

出版信息

Indian J Nucl Med. 2025 Jan-Feb;40(1):36-39. doi: 10.4103/ijnm.ijnm_105_24. Epub 2025 May 16.

DOI:10.4103/ijnm.ijnm_105_24
PMID:40453443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12121833/
Abstract

Invasive lobular carcinoma (ILC) of the breast is distinct among breast cancer subtypes due to its unique metastatic patterns, including the involvement of the liver, genital tract, and gastrointestinal tract. As ILC often exhibits low-grade fluorodeoxyglucose (FDG) avidity, the role of fluorine-18 FDG (F-18 FDG) positron emission tomography/computed tomography (PET/CT) in evaluating this subtype remains under re-explored. This case report highlights a rare presentation of ILC of the right breast with concurrent gastric and uterine metastases detected on F-18 FDG PET/CT, emphasizing its diagnostic utility.

摘要

乳腺浸润性小叶癌（ILC）在乳腺癌亚型中较为独特，因其具有独特的转移模式，包括肝脏、生殖道和胃肠道受累。由于ILC通常表现出低级别氟脱氧葡萄糖（FDG）摄取，氟-18 FDG（F-18 FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）在评估该亚型中的作用仍有待重新探索。本病例报告强调了F-18 FDG PET/CT检测到的右乳腺ILC并发胃和子宫转移的罕见表现，强调了其诊断效用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/476f/12121833/b1ee25631aae/IJNM-40-36-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/476f/12121833/8a344ce8cc38/IJNM-40-36-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/476f/12121833/13ac3ca776fc/IJNM-40-36-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/476f/12121833/b1ee25631aae/IJNM-40-36-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/476f/12121833/8a344ce8cc38/IJNM-40-36-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/476f/12121833/13ac3ca776fc/IJNM-40-36-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/476f/12121833/b1ee25631aae/IJNM-40-36-g003.jpg

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本文引用的文献

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The Influence of Tumor-Specific Markers in Breast Cancer on Other Blood Parameters.乳腺癌中肿瘤特异性标志物对其他血液参数的影响。
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Performance of [18F]FDG-PET/CT Imaging in First Recurrence of Invasive Lobular Carcinoma.[18F]氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描成像在浸润性小叶癌首次复发中的应用
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Clinical Significance of 18F-FDG-PET in Invasive Lobular Carcinoma.18F-FDG-PET在浸润性小叶癌中的临床意义
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Comparison of 18F-FDG PET/CT for Systemic Staging of Newly Diagnosed Invasive Lobular Carcinoma Versus Invasive Ductal Carcinoma.18F-FDG PET/CT用于新诊断的浸润性小叶癌与浸润性导管癌全身分期的比较
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Associations between the standardized uptake value of (18)F-FDG PET/CT and the prognostic factors of invasive lobular carcinoma: in comparison with invasive ductal carcinoma.（18）F-FDG PET/CT标准化摄取值与浸润性小叶癌预后因素的相关性：与浸润性导管癌的比较
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