从尼日利亚阿巴卡利基销售的肉类中分离出的耐头孢菌素弯曲杆菌属菌种的分布情况。
Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, Nigeria.
作者信息
Agumah Nnabuife Bernard, Effendi Mustofa Helmi, Tyasningsih Wiwiek, Witaningrum Adiana Mutamsari, Ugbo Emmanuel Nnabuike, Agumah Onyinyechi Blessing, Ahmad Riza Zainuddin, Nwagwu Chinekwu Sherridan, Ugbo Agatha Ifunanya, Khairullah Aswin Rafif, Moses Ikechukwu Benjamin, Yanestria Sheila Marty, Riwu Katty Hendriana Priscilia, Wasito Wasito
机构信息
Department of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria.
Division of Veterinary Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
出版信息
Open Vet J. 2025 Apr;15(4):1615-1623. doi: 10.5455/OVJ.2025.v15.i4.13. Epub 2025 Apr 30.
BACKGROUND
Campylobacter species have been at the forefront of the field as etiologic agents of foodborne gastroenteritis. The importance of animal proteins, especially contaminated meat, in the transmission of Campylobacteriosis cannot be overstated. Antimicrobial resistance by Campylobacter species is imminent, which underscores the importance of this study.
AIM
This study aimed to determine the antibiograms of Campylobacter species isolated from various meat samples sold in Abakaliki to select Cephalosporin antibiotics.
METHODS
We purchased 100 samples of various meat, Chevon (25), Pork (25), Beef (25), and Chicken (25) from four different market locations in Abakaliki. Culture and bacterial isolation were aseptically performed using standard bacteriological techniques. Campylobacter isolates obtained were confirmed using standard biochemical tests. Antibiotic susceptibility was assessed using Kirby Bauer's disc diffusion method. The selected cephalosporins used in this study included cefoxitin, ceftriazone, and cefepime. Aztreonam was used as a tangential control.
RESULTS
Our results showed that 69.0% of was isolated from this study, with chickens having the highest distribution (92.0%). The isolation percentage of was 55.0%, with chicken also exhibiting the highest distribution (80.0%). The Ishieke market had the highest distribution of (75.0%). The central abattoir had the highest distribution for (50.0%). Resistance recorded by to various antibiotics employed include; Cefoxitin (52.2%), Ceftriazone (55.1%), Cefepime (57.9%), and azatreonam (73.9%). The resistance of to various antibiotics employed include; Cefoxitin (45.5%), Ceftriazone (60.0%), Cefepime (63.6%), and azatreonam (56.4%).
CONCLUSION
The distribution of cephalosporin-resistant Campylobacter is high and represents a public health concern. More caution with hygiene and the use of antibiotics in animal husbandry is highly advocated.
背景
弯曲杆菌属一直是食源性肠胃炎病因研究领域的前沿对象。动物蛋白，尤其是受污染的肉类，在弯曲杆菌病传播中的重要性再怎么强调都不为过。弯曲杆菌属的抗菌耐药性问题迫在眉睫，这凸显了本研究的重要性。
目的
本研究旨在确定从阿巴卡利基销售的各种肉类样本中分离出的弯曲杆菌属的抗菌谱，以筛选头孢菌素类抗生素。
方法
我们从阿巴卡利基的四个不同市场地点购买了100份各种肉类样本，包括山羊肉（25份）、猪肉（25份）、牛肉（25份）和鸡肉（25份）。使用标准细菌学技术无菌进行培养和细菌分离。获得的弯曲杆菌分离株通过标准生化试验进行确认。使用 Kirby Bauer 纸片扩散法评估抗生素敏感性。本研究中使用的选定头孢菌素包括头孢西丁、头孢曲松和头孢吡肟。氨曲南用作平行对照。
结果
我们的结果表明，本研究分离出69.0%的[此处原文缺失具体菌种名称]，其中鸡肉的分布率最高（92.0%）。[此处原文缺失具体菌种名称]的分离率为55.0%，鸡肉的分布率也最高（80.0%）。伊希克市场[此处原文缺失具体菌种名称]的分布率最高（75.0%）。中央屠宰场[此处原文缺失具体菌种名称]的分布率最高（50.0%）。[此处原文缺失具体菌种名称]对所使用的各种抗生素的耐药率包括：头孢西丁（52.2%）、头孢曲松（55.1%）、头孢吡肟（57.9%）和氨曲南（73.9%）。[此处原文缺失具体菌种名称]对所使用的各种抗生素的耐药率包括：头孢西丁（45.5%）、头孢曲松（60.0%）、头孢吡肟（63.6%）和氨曲南（56.4%）。
结论
耐头孢菌素弯曲杆菌的分布率很高，这是一个公共卫生问题。强烈主张在畜牧业中更加注意卫生并谨慎使用抗生素。
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