Yamazaki K, Beauchamp G K, Thomas L, Boyse E A
J Exp Med. 1985 Oct 1;162(4):1377-80. doi: 10.1084/jem.162.4.1377.
Radiation chimeras were made by restoring lethally irradiated inbred mice with bone marrow cells of F1 hybrid mice of crosses between that inbred strain and an H-2-congenic strain. The urine of these chimeras was tested by the Y maze method, and shown to have acquired a scent indicative of the reconstituting donors' H-2 type. Thus, cells of the hematopoietic system contribute to the H-2-related odorant properties that enable mice to distinguish one another according to their H-2 types.
通过用该近交系与一个H-2同基因系杂交产生的F1杂种小鼠的骨髓细胞来恢复受到致死性照射的近交小鼠，从而制备辐射嵌合体。用Y迷宫法对这些嵌合体的尿液进行测试，结果显示其已获得一种表明重建供体H-2类型的气味。因此，造血系统的细胞对与H-2相关的气味特性有贡献，这些特性使小鼠能够根据其H-2类型相互区分。
