Petersen M, Hankinson J
J Occup Med. 1985 Sep;27(9):644-50.
Epidemiologic research into occupationally related lung disease often requires the comparison of a study population with an external reference group. To establish such a reference group, carefully selected blue-collar workers who had no obvious adverse occupational pulmonary exposure performed simple spirometry, were administered a standard questionnaire, and had standard chest roentgenograms taken. Prediction equations were established for six pulmonary function indices, and a method is given for using these equations to compare a study group with this external nonexposed group. Asymptomatic nonsmokers with negative roentgenograms were extracted from the overall group, and comparison with published data for other such normal groups indicated that the present group is similar to most of them, indicating that there are no serious biases in the present group.
对职业性肺病的流行病学研究通常需要将研究人群与外部参照组进行比较。为建立这样一个参照组,精心挑选了无明显不良职业性肺部暴露的蓝领工人,他们接受了简易肺量计检查、填写了标准问卷并拍摄了标准胸部X光片。针对六项肺功能指标建立了预测方程,并给出了一种使用这些方程将研究组与这个外部未暴露组进行比较的方法。从总体人群中提取出无症状、胸部X光片阴性的不吸烟者,与其他此类正常人群的已发表数据进行比较表明,本研究组与大多数此类人群相似,这表明本研究组不存在严重偏差。