Rodríguez-Blazquez Carmen, Aldridge Sarah J, Bernal-Delgado Enrique, Calomfirescu Cristian, Dolanski-Aghamanoukjan Lorenz, Estupiñán-Romero Francisco, Gissler Mika, Beate Gruber, Idavain Jane, Larose Tricia L, Lyons Ronan A, Mathis-Edenhofer Stefan, Miller Kristiina, Misiņš Jānis, Radulescu Silviu, Rätsep Merike, Sagerschnig Sophie, Sandu Petru, Šitcs Juris, Pavlovska Zane, Thißen Martin, Tolonen Hanna, Garriga Cesar, Forjaz Maria João
National Centre for Epidemiology, Carlos III Health Institute, Madrid, Spain.
Consortium Centre of Biomedical Research Network on Neurodegenerative Diseases (CIBERNED), Madrid, Spain.
Eur J Public Health. 2025 Jun 1;35(3):484-490. doi: 10.1093/eurpub/ckaf065.
In the framework of the European Population Health Information Research Infrastructure (PHIRI) project, we analysed the healthcare use for depression and/or anxiety during the coronavirus disease 2019 (COVID-19) pandemic. Aggregated monthly number of diagnoses were obtained from electronic health records and databases in Austria, Estonia, Finland, Latvia, Romania, Wales (UK), and Aragon (Spain) and analysed using the PHIRI federated research infrastructure. Rates of diagnosis, prescriptions and visits to primary care, hospital or emergency department were calculated by 10 000 population. Segmented Poisson regression to estimate changes in outcomes after the COVID-19 pandemic declaration was produced controlling for baseline levels and trends for the period January 2017 to December 2021. Following pandemic declaration, level change of incident diagnoses fell in Romania, Aragon (Spain), and Wales (UK) [log rate -0.853 (95% confidence interval -1.045 to -0.661), -0.338 (-0.434 to -0.242), and -0274 (-0.365 to -0.183), respectively]; level change of visits to primary care decreased in Romania and Wales (UK) [-0.347 (-0.555 to -0.138) and -0.272 (-0.368 to -0.177), respectively], and increased in Latvia [0.065 (0.004-0.126)]; level change for hospital admissions diminished in Latvia, Romania and Wales (UK) [-0.206 (-0.393 to -0.019), -0.947 (-1.143 to -0.752) and -0.116 (-0.202 to -0.030), respectively]; and level change of visits to emergency units fell in Latvia and Romania [-0.290 (-0.429 to -0.151) and -0.865 (-1.040 to -0.690), respectively] and increased in Aragon (Spain) [0.880 (0.259 to 1.502)]. COVID-19 pandemic declaration altered the use of mental health resources. This study highlights the potential use of harmonized data for providing evidence for future pandemic preparedness.
在欧洲人口健康信息研究基础设施(PHIRI)项目框架内,我们分析了2019年冠状病毒病(COVID-19)大流行期间抑郁症和/或焦虑症的医疗服务使用情况。从奥地利、爱沙尼亚、芬兰、拉脱维亚、罗马尼亚、威尔士(英国)和阿拉贡(西班牙)的电子健康记录和数据库中获取每月诊断总数,并使用PHIRI联合研究基础设施进行分析。按每10000人口计算诊断率、处方率以及到初级保健机构、医院或急诊科就诊的比率。通过分段泊松回归来估计COVID-19大流行声明发布后结果的变化,同时控制2017年1月至2021年12月期间的基线水平和趋势。在大流行声明发布后,罗马尼亚、阿拉贡(西班牙)和威尔士(英国)的新发诊断水平变化下降[对数率分别为-0.853(95%置信区间-1.045至-0.661)、-0.338(-0.434至-0.242)和-0.274(-0.365至-0.183)];罗马尼亚和威尔士(英国)到初级保健机构就诊的水平变化下降[分别为-0.347(-0.555至-0.138)和-0.272(-0.368至-0.177)],而拉脱维亚则上升[0.065(0.004至0.126)];拉脱维亚、罗马尼亚和威尔士(英国)的住院水平变化下降[分别为-0.206(-0.393至-0.019)、-0.947(-1.143至-0.752)和-0.116(-0.202至-0.030)];拉脱维亚和罗马尼亚到急诊科就诊的水平变化下降[分别为-0.290(-0.429至-0.151)和-0.865(-1.040至-0.690)],阿拉贡(西班牙)则上升[0.880(0.259至1.502)]。COVID-19大流行声明改变了心理健康资源的使用情况。本研究强调了统一数据在为未来大流行防范提供证据方面的潜在用途。