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骨内内镜辅助下病灶清创联合游离腓骨带血管移植治疗非创伤性股骨头坏死:与髓芯减压的对比研究

Intraosseous endoscopic-assisted lesion debridement combined with free fibular vascularized transplantation for non-traumatic femoral head necrosis: A comparative study with core decompression.

作者信息

Yang Yalong, Zhang Zhao, Wei Yuanyuan, Li Yang, Liu Junliang, Wang Bo, Mi Shouhu, Liu Jintong, Zhang Yongqiang, Guo Yongming, Wu Meng

机构信息

Department of Joint Surgery and Sports Medicine, Norinco General Hospital, Xi'an, China.

Department of Neurology, Norinco General Hospital, Xi'an, China.

出版信息

J Orthop Surg (Hong Kong). 2025 May-Aug;33(2):10225536251348726. doi: 10.1177/10225536251348726. Epub 2025 Jun 2.

Abstract

BackgroundNon-traumatic femoral head necrosis results from insufficient blood supply to the femoral head, causing hip pain, restricted movement, and eventual collapse. This study compares the efficacy of endoscopy-assisted lesion debridement with free vascularized fibular grafting versus core decompression (CD) to identify a more effective surgical approach for treating osteonecrosis of the femoral head (ONFH).MethodsThis retrospective study included 83 patients with femoral head necrosis who were treated between January 2010 and December 2020. The patients were divided into Group A (intraosseous endoscopic-assisted lesion debridement combined with free fibular grafting, = 45) and Group B (CD, = 38) based on their treatment approach. Preoperative general data, intraoperative variables such as operation time and blood loss, and postoperative assessments of Harris Hip Score, Visual Analog Scale (VAS), as well as imaging evaluations through X-ray and MRI for femoral head shape restoration and healing, were conducted at 1 week, 4 weeks, 3 months, 6 months, and 12 months post-surgery.ResultsA follow-up of more than 2 years was conducted for both groups of patients. Preoperative general data, such as age, showed no significant difference between the two groups ( > 0.05). Group A patients had significantly better Harris Hip Scores at 3, 6, and 12 months postoperatively, as well as significantly lower VAS scores at 4 weeks, 3 months, 6 months, and 12 months post-surgery compared to Group B ( < 0.05). In Group A, 3 patients experienced elevated body temperature (maximum 38.6°C), which was considered to be postoperative absorption heat; their temperatures returned to normal within 2-3 days following symptomatic treatment. All surgical incisions in both groups healed well, with no vascular or nerve injuries or other related complications. Additionally, imaging results showed that 4 hips in Group A developed femoral head collapse, compared to 10 hips in Group B. In Group A, 4 patients (4/45, 8.9%) with collapse were in ARCO stage II, while in Group B, 6 patients (6/38, 15.7%) were in ARCO stage I and 4 patients (4/38, 10.5%) were in ARCO stage II. Overall, Group A had a non-collapse rate of 91.1% (41/45) in early-stage femoral head necrosis, which was significantly higher than Group B's 73.7% (28/38) ( < 0.05).ConclusionIntraosseous Endoscopic-assisted lesion debridement combined with free fibular grafting shows superior clinical efficacy compared to CD in the treatment of femoral head necrosis. It effectively improves femoral head morphology, alleviates pain, restores joint function, and has a lower complication rate, making it a promising approach for further clinical application and promotion.

摘要

背景

非创伤性股骨头坏死是由于股骨头血液供应不足所致,会引起髋关节疼痛、活动受限,最终导致股骨头塌陷。本研究比较关节镜辅助下病灶清除联合游离血管腓骨移植与髓芯减压(CD)治疗股骨头坏死(ONFH)的疗效,以确定更有效的手术方法。

方法

本回顾性研究纳入了2010年1月至2020年12月期间接受治疗的83例股骨头坏死患者。根据治疗方法将患者分为A组(髓内关节镜辅助下病灶清除联合游离腓骨移植,n = 45)和B组(CD,n = 38)。记录术前一般资料、术中变量如手术时间和出血量,以及术后1周、4周、3个月、6个月和12个月时的Harris髋关节评分、视觉模拟量表(VAS)评估,以及通过X线和MRI对股骨头形态恢复和愈合情况的影像学评估。

结果

两组患者均进行了超过2年的随访。术前一般资料如年龄,两组间无显著差异(P > 0.05)。与B组相比,A组患者术后3个月、6个月和12个月时的Harris髋关节评分显著更高,术后4周、3个月、6个月和12个月时的VAS评分显著更低(P < 0.05)。A组有3例患者体温升高(最高38.6°C),考虑为术后吸收热;经对症治疗后,体温在2 - 3天内恢复正常。两组所有手术切口均愈合良好,无血管或神经损伤及其他相关并发症。此外,影像学结果显示,A组有4个股骨头发生塌陷,而B组有10个股骨头发生塌陷。A组中4例(4/45,8.9%)发生塌陷的患者处于ARCO II期,而B组中6例(6/38,15.7%)处于ARCO I期,4例(4/38,10.5%)处于ARCO II期。总体而言,A组早期股骨头坏死的无塌陷率为91.1%(41/45),显著高于B组的73.7%(28/38)(P < 0.05)。

结论

髓内关节镜辅助下病灶清除联合游离腓骨移植治疗股骨头坏死的临床疗效优于CD。它能有效改善股骨头形态,减轻疼痛,恢复关节功能,且并发症发生率较低,是一种有前景的方法,值得进一步临床应用和推广。

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