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阉割后大鼠附睾精子运输增强。

Enhancement of sperm transport through the rat epididymis after castration.

作者信息

Sujarit S, Pholpramool C

出版信息

J Reprod Fertil. 1985 Jul;74(2):497-502. doi: 10.1530/jrf.0.0740497.

DOI:10.1530/jrf.0.0740497
PMID:4045817
Abstract

Transport of spermatozoa through different regions of the epididymis has been followed by labelling testicular spermatozoa with [3H]thymidine in intact rats and in rats in which the efferent ducts were ligated or the testes were removed. In intact rats, the transit times of epididymal spermatozoa from the initial segment to the caput, from the caput to the corpus, and from the corpus to the cauda were 2, 4 and 2 days, respectively, giving a total transit time of 8 days. After bilateral castration, labelled spermatozoa were transferred from the initial segment into the proximal cauda by 2 days and appeared in the ductus deferens by 4 days. This effect was prevented by a daily subcutaneous injection of testosterone propionate (0.2 mg/kg). Bilateral efferent duct ligation had only a slight effect on the passage of epididymal spermatozoa. The results indicate that epididymal sperm transport is enhanced after androgen withdrawal.

摘要

在完整大鼠以及分别结扎输出小管或摘除睾丸的大鼠中,通过用[3H]胸腺嘧啶核苷标记睾丸精子,追踪了精子在附睾不同区域的运输情况。在完整大鼠中,附睾精子从起始段到附睾头、从附睾头到附睾体以及从附睾体到附睾尾的转运时间分别为2天、4天和2天,总转运时间为8天。双侧去势后,标记的精子在2天内从起始段转移至附睾尾近端,并在4天内出现在输精管中。每日皮下注射丙酸睾酮(0.2mg/kg)可阻止这种效应。双侧输出小管结扎对附睾精子的通过仅有轻微影响。结果表明,雄激素撤除后附睾精子运输增强。

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1
Enhancement of sperm transport through the rat epididymis after castration.阉割后大鼠附睾精子运输增强。
J Reprod Fertil. 1985 Jul;74(2):497-502. doi: 10.1530/jrf.0.0740497.
2
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Effects of caput ligation on rat sperm and epididymis: protein thiols and fertilizing ability.附睾头结扎对大鼠精子及附睾的影响:蛋白质巯基与受精能力
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Int J Androl. 1996 Dec;19(6):371-6. doi: 10.1111/j.1365-2605.1996.tb00530.x.

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