Hatz Laura E, Courtney Kelly E, Wallace Alexander L, Wade Natasha E, Baca Rachel, Doran Neal, Jacobus Joanna
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Veterans Affairs San Diego Healthcare System, La Jolla, CA, USA.
Front Adolesc Med. 2025;3. doi: 10.3389/fradm.2025.1486782. Epub 2025 Jan 20.
Nicotine and tobacco product (NTP) use in adolescence and young adulthood is associated with negative health and psychosocial outcomes. This study prospectively tested alcohol use, cannabis use, and peer and family NTP use as predictors of NTP use in adolescents and young adults (AYAs) who were NTP naïve or who primarily used electronic nicotine delivery systems (ENDS).
Participants (N=133) ages 16-22 completed a baseline laboratory visit and follow-up session one year later. Participants' baseline alcohol use, cannabis use, and NTP use by peers and family were tested as risk factors for any and moderate to heavy (at least monthly) NTP use at follow-up. Logistic regressions were conducted for the full sample (N=133) and in a subsample of participants reporting no to low NTP use at baseline (n=76).
Baseline alcohol use, cannabis use, and peer and family NTP use were associated with NTP use at one-year follow-up, over and above baseline NTP use. Peer and family NTP use emerged as the most consistent predictor of AYA NTP use (ORs: 4.059 - 8.432), while recent cannabis and alcohol use exerted effects (ORs: 1.003 - 1.021) that varied by NTP use level.
A confluence of variables, including prior substance use and social and familial influences, act as risk factors for NTP use in AYAs who primarily use ENDS. Identification of risk and protective factors for NTP use is necessary to inform efforts to decrease NTP use in this developmentally vulnerable population.
青少年和青年时期使用尼古丁及烟草制品（NTP）与负面健康和心理社会后果相关。本研究前瞻性地测试了酒精使用、大麻使用以及同伴和家庭的NTP使用情况，以此作为未使用过NTP或主要使用电子尼古丁传送系统（ENDS）的青少年和青年（AYA）使用NTP的预测因素。
16 - 22岁的参与者（N = 133）完成了一次基线实验室访视，并在一年后进行了随访。参与者的基线酒精使用、大麻使用以及同伴和家庭的NTP使用情况被作为随访时任何NTP使用以及中度至重度（至少每月一次）NTP使用的风险因素进行测试。对整个样本（N = 133）以及基线时报告未使用或低水平使用NTP的参与者子样本（n = 76）进行了逻辑回归分析。
基线酒精使用、大麻使用以及同伴和家庭的NTP使用与一年随访时的NTP使用相关，且超出了基线NTP使用的影响。同伴和家庭的NTP使用成为AYA使用NTP最一致的预测因素（比值比：4.059 - 8.432），而近期大麻和酒精使用的影响（比值比：1.003 - 1.021）因NTP使用水平而异。
包括先前物质使用以及社会和家庭影响在内的一系列变量，是主要使用ENDS的AYA使用NTP的风险因素。识别NTP使用的风险和保护因素对于为减少这一发育易损人群的NTP使用所做的努力提供信息是必要的。
