Iversen T
J Reprod Med. 1985 Aug;30(8):607-9.
Ninety-six patients with grade 3 cervical intraepithelial neoplasia (CIN) were treated with CO2 laser conization, and 45 were treated with cold-knife conization. Local anesthesia was used in 83% of the patients in the laser group; the rest received general anesthesia. In the laser group seven patients developed peri- and postoperative hemorrhages. Hemorrhages occurred among four of those treated with cold-knife conization. Laser conization with local anesthesia was well tolerated and can be recommended as an outpatient procedure for patients with endocervical grade 3 CIN or lesions suggestive of microinvasive cancer.
96例3级宫颈上皮内瘤变（CIN）患者接受了二氧化碳激光锥切术治疗，45例接受了冷刀锥切术治疗。激光组83%的患者采用局部麻醉，其余患者接受全身麻醉。激光组有7例患者发生围手术期出血。冷刀锥切术治疗的患者中有4例发生出血。局部麻醉下的激光锥切术耐受性良好，可推荐作为宫颈3级CIN或提示微浸润癌病变患者的门诊手术。
