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药用植物在隐孢子虫病治疗中的疗效:一项综合综述。

Efficacy of medicinal plants in cryptosporidiosis treatment: a comprehensive review.

作者信息

Thakur Shabnam, Yadav Richa, Kaur Upninder, Thakur J S, Sehgal Rakesh

机构信息

Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012 India.

Department of Microbiology, Aarupadai Veedu Medical College and Hospital (AVMC&H), Vinayaka Mission's Research Foundation-DU, Pondicherry, 607402 India.

出版信息

J Parasit Dis. 2025 Jun;49(2):273-280. doi: 10.1007/s12639-024-01769-w. Epub 2024 Dec 14.

Abstract

spp. infect the microvillus epithelial cells of the gastrointestinal tract of vertebrates. It leads to diarrheal disease named as cryptosporidiosis which is considered as the fifth leading cause of diarrhea in children younger than 5 years. The treatment is also limited, as there is only single FDA approved drug (i.e., Nitazoxanide) which has varying efficacy in immune-compromised individuals (HIV infections) and children. The increasing utilization of traditional plants extracts in treating these spp. of infectious protozoan parasite indicated their potentials as alternative remedies for dealing with these detrimental pathogens.

摘要

隐孢子虫属感染脊椎动物胃肠道的微绒毛上皮细胞。它会导致一种名为隐孢子虫病的腹泻疾病,该病被认为是5岁以下儿童腹泻的第五大主要病因。治疗方法也很有限,因为美国食品药品监督管理局(FDA)仅批准了一种药物(即硝唑尼特),该药物在免疫功能低下的个体(艾滋病毒感染)和儿童中的疗效各不相同。传统植物提取物在治疗这些传染性原生动物寄生虫方面的使用日益增加,表明它们有潜力成为应对这些有害病原体的替代疗法。

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