Saito Tetsuo
Division of Integrative Medical Oncology, Saiseikai Kumamoto Hospital, 5-3-1 Chikami, Minami-Ku, Kumamoto-Shi, Kumamoto, 861-4193, Japan.
Int J Clin Oncol. 2025 Jun 3. doi: 10.1007/s10147-025-02803-4.
As suggested by the findings of our previous investigations, palliative radiotherapy for painful lesions other than bone metastases may be as commonly used in clinical settings as it is for painful bone metastases (PBMs). Given the substantial number of patients requiring radiotherapy for painful non-bone-metastasis tumors (PNTs), the absence of specific clinical guidelines for this subset of patients poses a significant issue. This review aims to explore the effectiveness of palliative radiotherapy for PNTs and compare it to the well-established evidence supporting its use for PBMs. Additionally, the review discusses the optimal dose-fractionation schedules in palliative radiotherapy for the management of PNTs.
正如我们之前研究所发现的那样，姑息性放疗用于治疗除骨转移瘤之外的疼痛性病灶，在临床环境中的使用频率可能与用于治疗疼痛性骨转移瘤（PBMs）一样高。鉴于有大量患者需要针对疼痛性非骨转移瘤（PNTs）进行放疗，针对这部分患者缺乏具体的临床指南是一个重大问题。本综述旨在探讨姑息性放疗对PNTs的有效性，并将其与支持用于PBMs的充分证据进行比较。此外，该综述还讨论了姑息性放疗中用于治疗PNTs的最佳剂量分割方案。
