Vergara Piter Oliveira, Oliveira Jeronimo de Conto, Mattiello Rita, Montelongo Alfredo, Roman Rudi, Katz Natan, Wives Leandro Krug, Rados Dimitris Varvaki
Institute of Informatics, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Núcleo de Telessaúde do Rio Grande do Sul (TelessaúdeRS), Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
JAMA Netw Open. 2025 Jun 2;8(6):e2513285. doi: 10.1001/jamanetworkopen.2025.13285.
Integrating artificial intelligence (AI) technologies into gatekeeping holds significant potential, as it efficiently handles repetitive tasks and can process large amounts of information quickly.
To develop and assess the accuracy of an AI model that enhances the gatekeeping process for referrals to specialized care.
DESIGN, SETTING, AND PARTICIPANTS: This diagnostic study comprised referrals from primary care to endocrinology, gastroenterology, proctology, rheumatology, and urology from a retrospective administrative database of patients in Brazil between June 2016 and April 2019. Analysis was performed between December 2022 and July 2024.
The algorithm's development and testing comprised 2 stages. Multiple AI models were initially evaluated to train and test the algorithm for categorizing referrals as authorizing or requiring additional information. Subsequently, the model's performance was assessed against an independent set of referrals. Additionally, the current (human) evaluations of gatekeepers were evaluated against the standard. The reference standard was the consensus of 2 physicians with extensive experience. Accuracy, sensitivity, specificity, and area under the receiver operating characteristic curve (AUC-ROC) were assessed.
The electronic system retrieved 45 039 eligible referrals for the development stage (mean [SD] patient age, 51.9 [15.8] years; 25 458 women [56.5%]). An algorithm utilizing word embeddings and a neural network proved the most effective. In the second phase, 1750 referrals (350 for each specialty) showed a 32% authorization rate according to the reference standard. The AI model achieved an overall accuracy of 0.716 (95% IC, 0.694-0.737), with a sensitivity of 0.542 (95% CI, 0.501 to 0.582) and specificity of 0.801 (95% CI, 0.777 to 0.822). Regarding individual specialties, rheumatology exhibited the highest accuracy (0.811; 95% IC, 0.767-0.849), while proctology had the lowest (0.649; 95% IC, 0.597-0.697). The overall AUC-ROC was 0.765 (95% IC, 0.742-0.788). When compared against the consensus standard, the AI model had higher accuracy and specificity and lower sensitivity than the current approach.
In this diagnostic study of referral data, a novel AI model effectively distinguished between referrals that warranted immediate authorization and those that required further information with moderate accuracy; it had higher specificity and lower sensitivity than gatekeepers decisions. Implementing this AI model in the gatekeeping process should combine human judgment and AI support to optimize the referral process.
将人工智能(AI)技术整合到守门流程中具有巨大潜力,因为它能高效处理重复性任务并能快速处理大量信息。
开发并评估一种增强专科护理转诊守门流程的AI模型的准确性。
设计、背景和参与者:这项诊断性研究纳入了2016年6月至2019年4月巴西患者回顾性管理数据库中从初级保健转诊至内分泌科、胃肠病科、直肠科、风湿病科和泌尿科的病例。分析于2022年12月至2024年7月进行。
该算法的开发和测试包括两个阶段。最初评估了多个AI模型,以训练和测试将转诊分类为授权或需要额外信息的算法。随后,根据一组独立的转诊病例评估该模型的性能。此外,还对照标准评估了当前(人工)守门人的评估。参考标准是两位经验丰富的医生的共识。评估了准确性、敏感性、特异性和受试者操作特征曲线下面积(AUC-ROC)。
电子系统检索到45039例符合开发阶段要求的转诊病例(患者平均[标准差]年龄为51.9[15.8]岁;25458名女性[56.5%])。一种利用词嵌入和神经网络的算法被证明是最有效的。在第二阶段,1750例转诊病例(每个专科350例)根据参考标准显示授权率为32%。该AI模型的总体准确率为0.716(95%置信区间,0.694 - 0.737),敏感性为0.542(95%置信区间,0.501至0.582),特异性为0.801(95%置信区间,0.777至0.822)。就各个专科而言,风湿病科的准确率最高(0.811;95%置信区间,0.767 - 0.849),而直肠科最低(0.649;95%置信区间,0.597 - 0.697)。总体AUC-ROC为0.765(95%置信区间,0.742 - 0.788)。与共识标准相比,该AI模型的准确率和特异性更高,敏感性低于当前方法。
在这项转诊数据的诊断性研究中,一种新型AI模型能有效区分需要立即授权的转诊和需要进一步信息的转诊,准确性中等;其特异性高于守门人的决策,敏感性低于守门人的决策。在守门流程中实施此AI模型应将人工判断与AI支持相结合,以优化转诊流程。