Zhongguo Dang Dai Er Ke Za Zhi. 2025 May 15;27(5):505-514. doi: 10.7499/j.issn.1008-8830.2410119.
Thalassemia is a group of hereditary disorders characterized by ineffective erythropoiesis due to hemoglobin synthesis abnormalities, resulting in varying degrees of chronic anemia. Patients with transfusion-dependent thalassemia rely on lifelong regular blood transfusions and iron chelation therapy. Proper transfusion treatment and management of transfusion-related complications are essential to ensure the growth and development of pediatric patients and to improve their quality of life. The guideline working group has developed the guideline by referencing domestic and international guidelines, expert consensus, and relevant studies. The aim is to further standardize the transfusion management of transfusion-dependent thalassemia in children in China.
地中海贫血是一组遗传性疾病，其特征是由于血红蛋白合成异常导致红细胞生成无效，从而引起不同程度的慢性贫血。依赖输血的地中海贫血患者依靠终身定期输血和铁螯合疗法。适当的输血治疗和输血相关并发症的管理对于确保儿科患者的生长发育和提高其生活质量至关重要。指南工作组通过参考国内外指南、专家共识和相关研究制定了本指南。目的是进一步规范中国儿童依赖输血的地中海贫血的输血管理。
