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经皮冷冻神经lysis作为痉挛的动态治疗:病例系列

Percutaneous Cryoneurolysis as a Dynamic Treatment for Spasticity: A Case Series.

作者信息

Guynn Clay C

机构信息

Orthopaedics/Sports Medicine Deartment, Sports Medicine South of Gwinnett, Lawrenceville, GA.

出版信息

Arch Rehabil Res Clin Transl. 2025 Jan 6;7(1):100426. doi: 10.1016/j.arrct.2025.100426. eCollection 2025 Mar.

DOI:10.1016/j.arrct.2025.100426
PMID:40463785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12128593/
Abstract

Spasticity, whether from stroke or spinal cord injury or other causes, remains challenging to treat effectively. Common spasticity treatments such as stretching, physical therapy, injection therapy, and even surgery may not result in optimal or the desired outcomes or be appropriate for all patients. Cryoneurolysis is another potential treatment option for spasticity that may have benefits over traditional spasticity treatments. In this case series, 10 patients received cryoneurolysis of specific nerves to treat either lower or upper-extremity pain, weakness, and spasticity, or a neuropathic gait in an outpatient clinic. All 10 patients experienced immediate improvements that were sustained for 1-12 months after treatment. Cryoneurolysis is a safe and effective treatment for spasticity and can allow for easy access to involved nerves.

摘要

痉挛,无论源于中风、脊髓损伤还是其他原因,仍然难以得到有效治疗。常见的痉挛治疗方法,如拉伸、物理治疗、注射治疗,甚至手术,可能无法带来最佳或预期的效果,也并非适用于所有患者。冷冻神经溶解术是痉挛的另一种潜在治疗选择,可能比传统的痉挛治疗方法更具优势。在这个病例系列中,10名患者在门诊接受了特定神经的冷冻神经溶解术,以治疗下肢或上肢疼痛、无力、痉挛或神经性步态。所有10名患者均立即出现改善,且在治疗后持续了1至12个月。冷冻神经溶解术是一种安全有效的痉挛治疗方法,并且能够方便地触及受累神经。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/c50fcd1b136c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/b3202e249944/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/a9a5e0f734e5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/66a4dc9b592a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/c50fcd1b136c/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/b3202e249944/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/a9a5e0f734e5/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/66a4dc9b592a/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96fd/12128593/c50fcd1b136c/gr4.jpg

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本文引用的文献

1
Measuring the Efficacy of Percutaneous Cryoneurolysis in Participants With Refractory or Plateaued Shoulder, Elbow, Wrist, or Finger Spasticity.评估经皮冷冻神经lysis术对难治性或平台期肩部、肘部、腕部或手指痉挛患者的疗效。 (注:原文中“Cryoneurolysis”未查到准确对应中文,暂保留英文)
Am J Phys Med Rehabil. 2025 Mar 28. doi: 10.1097/PHM.0000000000002728.
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Cryoneurolysis of the Femoral Nerve for Focal Spasticity in an Ambulatory Patient.门诊患者股神经冷冻神经lysis治疗局灶性痉挛
Arch Rehabil Res Clin Transl. 2024 Jan 5;6(1):100319. doi: 10.1016/j.arrct.2024.100319. eCollection 2024 Mar.
3
Recommendations for Ultrasound Guidance for Diagnostic Nerve Blocks for Spasticity. What Are the Benefits?
超声引导下痉挛诊断性神经阻滞的推荐意见。有何益处?
Arch Phys Med Rehabil. 2023 Sep;104(9):1539-1548. doi: 10.1016/j.apmr.2023.01.011. Epub 2023 Feb 4.
4
Cryoneurolysis of Anterior and Posterior Divisions of the Obturator Nerve.闭孔神经前支和后支的冷冻神经lysis(这个词可能有误,正确的可能是lysis,即溶解、分解等意思,这里暂按原词翻译为冷冻神经lysis)
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Arch Rehabil Res Clin Transl. 2019 Oct 17;1(3-4):100030. doi: 10.1016/j.arrct.2019.100030. eCollection 2019 Dec.
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Novel cryoneurolysis device for the treatment of sensory and motor peripheral nerves.用于治疗感觉和运动性周围神经的新型冷冻神经lysis装置。 (注:“lysis”常见释义为“分解、溶解” ,这里结合语境,可能是冷冻神经溶解之类的专业说法,但因专业领域可能有特定含义,整体译文可能需根据医学专业知识进一步优化。)
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Complications of intrathecal baclofen pump therapy in pediatric patients.小儿鞘内注射巴氯芬泵治疗的并发症
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J Neural Transm (Vienna). 2008;115(4):617-23. doi: 10.1007/s00702-007-0869-3. Epub 2008 Mar 6.