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[干眼症]

[The dry eye].

作者信息

Royer J

出版信息

Klin Monbl Augenheilkd. 1985 Jun;186(6):436-41. doi: 10.1055/s-2008-1050953.

Abstract

Dry eye, or keratoconjunctivitis sicca, is a pathologic condition which, today, needs to be more precisely defined. The moisture in the eye, which is essential for optical and physiological reasons, is maintained by three factors: a) the secretion of mucus by the conjunctiva, rendering uniform distribution of the aqueous phase of the lacrimal film on the corneal surface possible; b) the secretion of aqueous humor by the lacrimal and conjunctival glands; and c) the secretion of lipids from the skin and meibomian glands. Accordingly, an insufficiency of the lacrimal film may be due to insufficient secretion of lipids from the skin or meibomian glands, insufficiency of the aqueous phase of the lacrimal film (as is the case in Gougerot-Sjögren syndrome), or insufficiency of the mucus secretions (as in the case of pemphigoid syndrome). The complaints which lead patients to consult an ophthalmologist, as well as the objective findings on examination, are described here. The methods of examination by which lacrimal insufficiency can be confirmed are discussed: Schirmer's test (I and II), Jones' test, Norn's dilution test, break-up time, tests with dyes such as fluorescein, rose bengal, and lissamine green 1%. The conjunctival imprint gives indications without which no clear diagnosis can be made. The treatment of dry eye consists primarily of instillations of artificial tears. If this treatment fails the lacrimal puncta can be closed. Thirdly, pathogenic treatments can be used in certain cases. Fourthly, one can prescribe closed frames which create a wetting chamber. Finally, in particularly severe cases, surgery can be considered.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

干眼症,即角结膜干燥症,是一种病理状态,如今需要更精确地定义。眼睛中的水分对于视觉和生理功能至关重要,其由三个因素维持:a)结膜分泌黏液,使泪膜水相在角膜表面均匀分布成为可能;b)泪腺和结膜腺分泌房水;c)皮肤和睑板腺分泌脂质。因此,泪膜不足可能是由于皮肤或睑板腺分泌脂质不足、泪膜水相不足(如 Gougerot-Sjögren 综合征的情况)或黏液分泌不足(如类天疱疮综合征的情况)。本文描述了导致患者咨询眼科医生的症状以及检查时的客观发现。讨论了可用于确诊泪液不足的检查方法:Schirmer 试验(I 和 II)、Jones 试验、Norn 稀释试验、泪膜破裂时间、使用荧光素、孟加拉玫瑰红和 1%丽丝胺绿等染料的试验。结膜印迹可提供诊断依据,否则无法做出明确诊断。干眼症的治疗主要包括滴入人工泪液。如果这种治疗无效,可以封闭泪小点。第三,在某些情况下可采用病因治疗。第四,可以开处方佩戴能形成湿润腔室的封闭式眼镜架。最后,在特别严重的情况下,可以考虑手术治疗。(摘要截选至 250 字)

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