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对接受和未接受角膜交联的圆锥角膜患者在瓦尔萨尔瓦动作期间眼前段和角膜变化的评估。

An evaluation of anterior segment and corneal changes during the valsalva maneuver in keratoconus patients with and without corneal cross-linking.

作者信息

Mutaf Çağrı, Uzun Irfan, Reyhan Ali Hakim, Yüksekyayla Funda

机构信息

Department of Ophthalmology, Harran University Faculty of Medicine, Osmanbey Campus, Haliliye, 63300, Sanliurfa, Turkey.

出版信息

Int Ophthalmol. 2025 Jun 4;45(1):224. doi: 10.1007/s10792-025-03618-y.

DOI:10.1007/s10792-025-03618-y
PMID:40468035
Abstract

AIMS

To evaluate the effects of the Valsalva maneuver on the anterior segment and cornea in keratoconus patients with and without corneal crosslinking.

METHODS

Forty-five eyes of 45 keratoconus patients who underwent corneal cross-linking and 45 eyes of 45 keratoconus patients who did not undergo the procedure were included. Anterior keratometry values (K-flat, K-steep, and K-max), central corneal thickness, corneal apex thickness, thinnest corneal thickness, corneal volume, anterior chamber volume (ACV), anterior chamber depth (ACD), and iridocorneal angle (ICA) values were measured using a Pentacam Scheimpflug camera (Oculus, Germany) before and during the Valsalva maneuver. Changes in the anterior segment parameters from baseline and during the Valsalva maneuver, and the differences in the parameters between the keratoconus groups with and without corneal cross-linking were determined. A p value less than 0.05 was considered statistically significant.

RESULTS

ACV, ACD, and ICA decreased significantly during the Valsalva maneuver. However, the maneuver had no particular effect on corneal parameters in keratoconus patients (p > 0.05). The changes induced by the Valsalva maneuver were not statistically significant for any parameters in either group of patients with keratoconus.

CONCLUSIONS

The Valsalva maneuver does not lead to significant changes in keratoconus patients with or without corneal cross-linking.

摘要

目的

评估瓦尔萨尔瓦动作对接受和未接受角膜交联的圆锥角膜患者眼前节和角膜的影响。

方法

纳入45例接受角膜交联的圆锥角膜患者的45只眼以及45例未接受该手术的圆锥角膜患者的45只眼。在瓦尔萨尔瓦动作前及动作过程中,使用Pentacam眼前节分析系统(德国奥culus公司)测量角膜前表面曲率值(平坦K值、陡峭K值和最大K值)、中央角膜厚度、角膜顶点厚度、最薄角膜厚度、角膜体积、前房体积(ACV)、前房深度(ACD)和虹膜角膜角(ICA)值。确定眼前节参数从基线到瓦尔萨尔瓦动作过程中的变化,以及接受和未接受角膜交联的圆锥角膜组之间参数的差异。p值小于0.05被认为具有统计学意义。

结果

在瓦尔萨尔瓦动作过程中,ACV、ACD和ICA显著降低。然而,该动作对圆锥角膜患者的角膜参数没有特别影响(p>0.05)。瓦尔萨尔瓦动作引起的变化在两组圆锥角膜患者的任何参数中均无统计学意义。

结论

瓦尔萨尔瓦动作不会导致接受或未接受角膜交联的圆锥角膜患者出现显著变化。

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本文引用的文献

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Effect of refractive status on Valsalva-induced anterior segment changes.屈光状态对瓦尔萨尔瓦动作诱发的眼前节变化的影响。
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Eye Contact Lens. 2017 Sep;43(5):308-312. doi: 10.1097/ICL.0000000000000269.
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Long-term results of Nd:YAG laser treatment for premacular subhyaloid haemorrhage owing to Valsalva retinopathy.钕钇铝石榴石激光治疗瓦尔萨尔瓦视网膜病变所致黄斑前玻璃体下出血的长期结果
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