Department of Ophthalmology, GATA Haydarpasa Training Hospital, Uskudar, Istanbul, Turkey.
Graefes Arch Clin Exp Ophthalmol. 2010 Aug;248(8):1183-6. doi: 10.1007/s00417-010-1359-0. Epub 2010 Mar 24.
To evaluate the effect of the Valsalva maneuver (VM) on short-term variations of intraocular pressure (IOP) and ocular pulse amplitude (OPA) values in healthy, young, male subjects.
IOP and OPA values were measured before and during VM by Pascal dynamic contour tonometer (DCT) in 55 eyes of 55 healthy male volunteers aged 20 through 27 years.
Mean IOP before VM was 17.2 +/- 2.9 mmHg and during the VM was 19.8 +/- 4 mmHg. The increase in mean IOP during the VM was found to be statistically significant (p = 0.001). The IOP increased in 46 (83.6%) of 55 eyes. However, in nine eyes (16.4%), IOP decreased during the VM. Mean OPA value before VM was 3.6 +/- 1.4 mmHg and during the VM was 3.6 +/- 1.3 mmHg. The change in mean OPA value was found to be statistically insignificant (p = 0.9).
The IOP significantly increases during VM, whereas OPA remains stable. Strong autoregulatory mechanisms may provide consistent ocular perfusion in healthy subjects during VM.
评估瓦尔萨尔瓦动作(VM)对健康年轻男性受试者的眼内压(IOP)和眼脉冲幅度(OPA)短期变化的影响。
通过帕斯卡动态轮廓眼压计(DCT)在 55 名 20 至 27 岁健康男性志愿者的 55 只眼中测量 VM 前后的 IOP 和 OPA 值。
VM 前平均 IOP 为 17.2 +/- 2.9 mmHg,VM 期间为 19.8 +/- 4 mmHg。VM 期间平均 IOP 的增加具有统计学意义(p = 0.001)。在 55 只眼中的 46 只(83.6%)中,IOP 增加。然而,在 9 只眼(16.4%)中,IOP 在 VM 期间下降。VM 前平均 OPA 值为 3.6 +/- 1.4 mmHg,VM 期间为 3.6 +/- 1.3 mmHg。平均 OPA 值的变化无统计学意义(p = 0.9)。
IOP 在 VM 期间显着增加,而 OPA 保持稳定。在 VM 期间,强大的自动调节机制可能为健康受试者提供一致的眼部灌注。