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骨质疏松性椎体压缩骨折椎体强化术中骨水泥分布模式的系统评价

Bone cement distribution patterns in vertebral augmentation for osteoporotic vertebral compression fractures: a systematic review.

作者信息

Yang Kangjia, Zhu Xingyu, Sun Xiaopeng, Shi Hang, Sun Lixuan, Ding Hua

机构信息

Department of Orthopedics, Affiliated People's Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212002, China.

出版信息

J Orthop Surg Res. 2025 Jun 4;20(1):568. doi: 10.1186/s13018-025-05868-z.

Abstract

BACKGROUND

Osteoporotic vertebral compression fractures (OVCFs) are common in osteoporosis patients. Vertebral augmentation procedures like percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) are widely used, but the impact of bone cement distribution patterns on treatment efficacy remains unclear, and there is a lack of unified classification criteria.

METHODS

A systematic search was conducted in multiple databases, including PubMed, Web of Science, EMBASE, and CENTRAL until September 30, 2024. Studies on OVCF patients who underwent vertebral augmentation, described cement distribution patterns, and provided clinical data were included. Data extraction and quality assessment were performed following PRISMA guidelines.

RESULTS

After screening 408 papers, 21 studies with 3997 patients were included. Morphological classifications showed that a diffuse spongy distribution pattern was associated with better clinical outcomes. Directional classifications indicated that bilateral and even cement distribution led to better vertebral height restoration and pain relief. Sufficient cement distribution was crucial for treatment success, and cement contact with both upper and lower endplates reduced refracture risk.

CONCLUSIONS

Cement distribution patterns significantly affect OVCF treatment efficacy. Current classifications lack standardization, necessitating objective assessment tools and large-scale studies to optimize surgical techniques and patient outcomes.

摘要

背景

骨质疏松性椎体压缩骨折(OVCFs)在骨质疏松患者中很常见。椎体强化手术,如经皮椎体成形术(PVP)和经皮后凸成形术(PKP)被广泛应用,但骨水泥分布模式对治疗效果的影响仍不清楚,且缺乏统一的分类标准。

方法

在多个数据库中进行系统检索,包括PubMed、Web of Science、EMBASE和CENTRAL,检索截至2024年9月30日的文献。纳入对接受椎体强化治疗的OVCF患者进行研究,描述骨水泥分布模式并提供临床数据的文献。按照PRISMA指南进行数据提取和质量评估。

结果

在筛选408篇论文后,纳入了21项研究,共3997例患者。形态学分类显示,弥漫性海绵状分布模式与更好的临床结果相关。方向性分类表明,双侧且均匀的骨水泥分布可带来更好的椎体高度恢复和疼痛缓解。足够的骨水泥分布对治疗成功至关重要,骨水泥与上下终板接触可降低再骨折风险。

结论

骨水泥分布模式显著影响OVCF的治疗效果。目前的分类缺乏标准化,需要客观评估工具和大规模研究来优化手术技术和患者预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8e9/12135570/337b9b6ef4f0/13018_2025_5868_Fig1_HTML.jpg

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