Hermes-Pereira Andressa, Goulart Mariana, Kochhann Renata, Schumacher-Schuh Artur Francisco
Universidade Federal do Rio Grande do Sul, Rio Grande do Sul RS, Brazil.
Pontifícia Universidade Católica do Rio Grande do Sul, Rio Grande do Sul RS, Brazil.
Dement Neuropsychol. 2025 Jun 2;19:e20240190. doi: 10.1590/1980-5764-DN-2024-0190. eCollection 2025.
Neuropsychiatric symptoms of dementia, also known as behavioral and psychological symptoms of dementia, are extremely common. These symptoms represent one of the main causes of burden and distress among caregivers and can lead to decline in their physical and mental health.
This study aimed to identify predominant characteristics in a sample of Brazilian outpatient dementia patients and explore which symptoms exert the greatest influence on caregiver burden.
This was a cross-sectional study involving 119 caregivers. Stepwise regression analysis was used, with caregiver burden as the dependent variable and depressive symptoms, caregiver distress due to neuropsychiatric symptoms, and quality of life as independent variables in the final model.
Regression analysis identified three different models as predictors of caregiver burden. The first model, composed of depressive symptoms, predicted 34% of caregiver burden (p≤0.000). The second model, composed of depressive symptoms and caregiver distress due to neuropsychiatric symptoms, predicted 49% (p≤0.000). The third model, composed of depressive symptoms, caregiver distress due to neuropsychiatric symptoms, and quality of life, predicted 52% (p≤0.008).
Our findings indicate that problematic behaviors in dementia patients, depressive symptoms, and quality of life are associated with the level of caregiver burden and distress. Further research is needed to differentiate these findings among different types of dementia and to better understand how caregivers' individual characteristics influence their own burden.
痴呆的神经精神症状,也称为痴呆的行为和心理症状,极为常见。这些症状是照料者负担和痛苦的主要原因之一,可导致他们身心健康下降。
本研究旨在确定巴西门诊痴呆患者样本中的主要特征,并探讨哪些症状对照料者负担影响最大。
这是一项涉及119名照料者的横断面研究。采用逐步回归分析,在最终模型中,将照料者负担作为因变量,抑郁症状、神经精神症状导致的照料者痛苦和生活质量作为自变量。
回归分析确定了三种不同模型作为照料者负担的预测因素。第一个模型由抑郁症状组成,预测了34%的照料者负担(p≤0.000)。第二个模型由抑郁症状和神经精神症状导致的照料者痛苦组成,预测了49%(p≤0.000)。第三个模型由抑郁症状、神经精神症状导致的照料者痛苦和生活质量组成,预测了52%(p≤0.008)。
我们的研究结果表明,痴呆患者的问题行为、抑郁症状和生活质量与照料者负担和痛苦程度相关。需要进一步研究以区分不同类型痴呆中的这些发现,并更好地理解照料者的个体特征如何影响其自身负担。