Asaduzzaman Md, Khan Emil Arham, Hasan Mohammad Nayeem, Rahman Mahbubur, Ashrafi Shah Ali Akbar, Haque Farhana, Haider Najmul
Department of Engineering, University of Staffordshire, Stoke on Trent, UK.
Westlake High School, 4100 Westbank Drive, Austin, TX 78746, USA.
IJID Reg. 2025 Apr 22;15:100654. doi: 10.1016/j.ijregi.2025.100654. eCollection 2025 Jun.
In 2023, Bangladesh faced the largest dengue outbreak, resulting in 321,179 confirmed cases and 1705 fatalities. This study aims to characterize dengue fatalities and analyze their determinants and spatial influence.
Using data from the Management Information System of the Ministry of Health and Family Welfare, we characterized dengue mortality and conducted a linear regression analysis to determine the impact of age groups and gender on case fatality rate (CFR). We used a geographically weighted Poisson regression model to assess the spatial influence and impact of population factors.
Women had a higher CFR than men (0.75% vs 0.38%, <0.05). Among the recorded deaths, 74% (n = 1262) developed dengue shock syndrome, 17% (n = 290) expanded dengue syndrome, and 7% (n = 119) dengue hemorrhagic fever. The 10-year age groups significantly impacted CFR (estimate: 0.03, <0.01), suggesting that each additional decade increased CFR by 30%, whereas gender was insignificant. Higher deaths were observed in the southern regions, whereas spatial clusters were primarily concentrated around Dhaka City, the epicenter of the outbreak. Substantial effects from neighboring districts were also identified.
Bangladesh's 2023 dengue outbreak resulted in significant mortality, particularly, among older age groups. Fatalities were clustered in Dhaka City and its neighboring districts, especially in the south.
2023年，孟加拉国面临最大规模的登革热疫情，确诊病例达321,179例，死亡1705例。本研究旨在描述登革热死亡情况，分析其决定因素和空间影响。
利用卫生和家庭福利部管理信息系统的数据，我们描述了登革热死亡率，并进行线性回归分析以确定年龄组和性别对病死率（CFR）的影响。我们使用地理加权泊松回归模型来评估人口因素的空间影响和作用。
女性的病死率高于男性（0.75%对0.38%，<0.05）。在记录的死亡病例中，74%（n = 1262）出现登革热休克综合征，17%（n = 290）出现重症登革热综合征，7%（n = 119）出现登革出血热。10岁年龄组对病死率有显著影响（估计值：0.03，<0.01），表明每增加一个十年，病死率增加30%，而性别影响不显著。南部地区死亡人数较多，而空间聚集主要集中在疫情中心达卡市周围。还发现了邻近地区的显著影响。
孟加拉国2023年的登革热疫情导致了显著死亡，尤其是在老年人群体中。死亡病例集中在达卡市及其邻近地区，特别是南部地区。
