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塞拉利昂一家农村医院女性性传播感染情况:一项回顾性数据库研究

Sexually transmitted infections in women in a rural hospital in Sierra Leone: a retrospective database study.

作者信息

Kanu Emmanuel Marx, Rottmann Henning, Olaru Ioana D, Theiler Tom, Kargbo Islam M, Mathéron Hanna M, Kalkman Laura C, Grobusch Martin P, Schaumburg Frieder

机构信息

Masanga Medical Research Unit, Masanga Teaching Hospital, Tonkolili District, Sierra Leone.

Centre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Faculty of Medicine, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.

出版信息

IJID Reg. 2025 Apr 17;15:100652. doi: 10.1016/j.ijregi.2025.100652. eCollection 2025 Jun.

Abstract

OBJECTIVES

This study aimed to determine the frequency of sexually transmitted infections among women of reproductive age in a rural hospital in Sierra Leone.

METHODS

This retrospective cross-sectional database study included vaginal and endocervical swabs from 104 women of childbearing age (March 2023-March 2024) in Masanga Teaching Hospital, rural Sierra Leone. Samples were screened by loop-mediated isothermal amplification (eazyplex STD complete) for , and Demographic and medical data were obtained from medical records.

RESULTS

The median age was 26 years (range: 21-33 years). HIV status was available for 84 women, of whom nine (11%) were HIV-positive. Of the 75 women with clinical information available, 73 (97%) were symptomatic. Vaginal discharge (n = 66 of 75, 88%) was the most frequently reported symptom. Tests were positive for at least one target organism in the test panel in 54 of 104 cases (52%). was most often detected (n = 47 of 104, 45% followed by (n = 18 of 104, 17%) and (n = 3 of 104, 3%), whereas and were positive in one (1%) sample each. was not detected.

CONCLUSIONS

The detection of obligate sexually transmitted infections pathogens (i.e. ; n = 5 of 104, 5%) was rare in our study population and setting.

摘要

目的

本研究旨在确定塞拉利昂一家农村医院育龄妇女中性传播感染的发生率。

方法

这项回顾性横断面数据库研究纳入了塞拉利昂农村马桑加教学医院104名育龄妇女(2023年3月至2024年3月)的阴道和宫颈拭子。样本通过环介导等温扩增法(eazyplex STD complete)进行筛查, 并从病历中获取人口统计学和医疗数据。

结果

中位年龄为26岁(范围:21 - 33岁)。84名女性的艾滋病毒感染状况已知,其中9名(11%)为艾滋病毒阳性。在有临床信息的75名女性中,73名(97%)有症状。阴道分泌物(75名中有66名,88%)是最常报告的症状。104例中有54例(52%)检测出至少一种检测 panel 中的目标病原体呈阳性。 最常被检测到(104例中有47例,45%),其次是 (104例中有18例,17%)和 (104例中有3例,3%),而 和 在各1个(1%)样本中呈阳性。 未被检测到。

结论

在我们的研究人群和环境中,专性传播感染病原体(即 ;104例中有5例,5%)的检测很少见。

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