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一项为期12周的肥胖干预对绝经各阶段更年期症状及心理健康的影响:一项横断面分析

Impact of a 12-week obesity intervention on menopausal symptoms and psychological well-being across menopause stages: a cross-sectional analysis.

作者信息

Kumar Rupal, Rizvi Moattar Raza, Sami Waqas

机构信息

Department of Nutrition and Dietetics, School of Allied Health Sciences, Manav Rachna International Institute of Research and Studies, Faridabad, India.

College of Healthcare Professions (CoHP), D.I.T University, Dehradun, India.

出版信息

Front Reprod Health. 2025 May 21;7:1524790. doi: 10.3389/frph.2025.1524790. eCollection 2025.

Abstract

INTRODUCTION

Menopause poses unique physical and psychological challenges, especially for obese women, impacting quality of life across menopausal stages. This study evaluates a 12-week obesity educator program on body composition, menopausal symptoms, and psychological well-being among pre-, peri-, and post-menopausal obese women in Delhi NCR, India.

METHODS

A cross-sectional analysis was conducted with 291 obese women (97 per menopausal stage) assessing anthropometric measures, menopausal symptoms via the Menopause Rating Scale (MRS), and psychological well-being using the Well-being Questionnaire (W-BQ12). Data were analyzed using paired t-tests, ANCOVA, Pearson's correlation, and regression analysis.

RESULTS

The intervention led to significant weight reduction across all groups (3.8-4.5 kg,  < 0.001), waist circumference decreases (5.7-6.5 cm,  < 0.001), and HbA1c reductions by 0.4% ( < 0.001). Regression analysis identified waist-to-hip ratio and hemoglobin as predictors of somato-vegetative and psychological symptoms (  = 0.15,  < 0.05). MRS scores showed the most improvement in perimenopausal women.

CONCLUSION

The obesity educator program effectively improved body composition, glycemic control, and well-being across menopausal stages, highlighting the value of personalized interventions for menopausal health management.

摘要

引言

更年期带来了独特的身体和心理挑战,尤其是对于肥胖女性而言,这会影响整个更年期阶段的生活质量。本研究评估了一项为期12周的肥胖教育项目对印度新德里国家首都辖区绝经前、围绝经期和绝经后肥胖女性的身体成分、更年期症状及心理健康的影响。

方法

对291名肥胖女性(每个更年期阶段97名)进行横断面分析,评估人体测量指标、通过更年期评定量表(MRS)评估更年期症状以及使用幸福感问卷(W-BQ12)评估心理健康状况。数据采用配对t检验、协方差分析、Pearson相关性分析和回归分析。

结果

干预导致所有组体重显著减轻(3.8 - 4.5千克,<0.001),腰围减小(5.7 - 6.5厘米,<0.001),糖化血红蛋白降低0.4%(<0.001)。回归分析确定腰臀比和血红蛋白是躯体植物神经症状及心理症状的预测因素(=0.15,<0.05)。围绝经期女性的MRS评分改善最为明显。

结论

肥胖教育项目有效改善了各更年期阶段女性的身体成分、血糖控制和幸福感,凸显了个性化干预对更年期健康管理的价值。

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