Ji Tong, Li Yun, Ma Lina
Department of Geriatrics, Xuanwu Hospital, Capital Medical University, National Research Center for Geriatric Medicine, Beijing 100053, China.
Aging Dis. 2022 Apr 1;13(2):379-388. doi: 10.14336/AD.2021.1006. eCollection 2022 Apr.
Population aging and the obesity epidemic are important global public health problems that pose an unprecedented threat to the physical and mental health of the elderly and health systems worldwide. Sarcopenic obesity (SO) is a new category of obesity and a high-risk geriatric syndrome in the elderly. SO is associated with many adverse health consequences such as frailty, falls, disability, and increased morbidity and mortality. The core mechanism of SO is the vicious circle between myocytes and adipocytes. In order to implement effective prevention and treatment strategies and reduce adverse clinical outcomes, it is essential to further our understanding of SO in the elderly. Herein, we reviewed the definition, diagnosis, epidemiology, pathogenesis, and treatment of SO in older adults.
人口老龄化和肥胖流行是重要的全球公共卫生问题，对全球老年人的身心健康及卫生系统构成了前所未有的威胁。肌少症性肥胖（SO）是肥胖的一种新类型，也是老年人中的一种高危老年综合征。SO与许多不良健康后果相关，如身体虚弱、跌倒、残疾以及发病率和死亡率增加。SO的核心机制是肌细胞和脂肪细胞之间的恶性循环。为了实施有效的预防和治疗策略并减少不良临床结局，进一步了解老年人的SO至关重要。在此，我们综述了老年人SO的定义、诊断、流行病学、发病机制和治疗。
