• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种有效的耳部瘢痕疙瘩治疗方法:切除原发病灶及术后使用皮质类固醇激素

An Effective Auricular Keloids Management Method: Excision of the Original Lesion and Postoperative Corticosteroids.

作者信息

Luo Jing, Huang Jingyan, Yang Jun, Gao Zhen, Wang Xiuxia

机构信息

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, People's Republic of China.

出版信息

Aesthetic Plast Surg. 2025 Jun 5. doi: 10.1007/s00266-025-04925-6.

DOI:10.1007/s00266-025-04925-6
PMID:40471245
Abstract

BACKGROUND

Auricular keloids are challenging to manage, and recurrent keloids are more aggressive and likely to cause auricular deformities. Monotherapy such as surgical resection, injection, or radiotherapy alone has a high recurrence rate. The treatment approach for auricular keloids remains to be investigated.

METHODS

A retrospective analysis was conducted on 30 patients who received treatment at the Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, between December 2021 and May 2023. Based on the size, location, and extent of keloid invasion, the appearance of auricle was reconstructed by repairing scar flap after excision of the keloid and its core or resection. Postoperative injections of triamcinolone were administered within one week after suture removal, followed by every two weeks for 4-6 times.

RESULTS

30 patients were followed up for 6-36 months after the operation. The POSAS score of the patients was significantly lower than that before the operation. Among them, one patient relapsed due to failure to receive regular postoperative injections, one patient experienced delayed healing due to local hair interference, and two patients had menstrual disorders during the injection.

CONCLUSION

For keloids with diverse morphologies and anatomic locations, adopting individualized combined treatment involving surgical excision and intralesional triamcinolone acetonide injections can achieve the reconstruction of auricle morphology and maintain a long-term therapeutic effect.

LEVEL OF EVIDENCE IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors   www.springer.com/00266 .

摘要

背景

耳部瘢痕疙瘩的治疗具有挑战性,复发性瘢痕疙瘩更具侵袭性,且可能导致耳部畸形。单纯手术切除、注射或放疗等单一疗法的复发率很高。耳部瘢痕疙瘩的治疗方法仍有待研究。

方法

对2021年12月至2023年5月期间在上海第九人民医院整复外科接受治疗的30例患者进行回顾性分析。根据瘢痕疙瘩的大小、位置和侵袭范围,在切除瘢痕疙瘩及其核心或进行切除后,通过修复瘢痕皮瓣重建耳廓外观。术后在拆线后1周内注射曲安奈德,随后每2周注射1次,共注射4 - 6次。

结果

30例患者术后随访6 - 36个月。患者的POSAS评分显著低于术前。其中,1例患者因未接受定期术后注射而复发,1例患者因局部毛发干扰导致愈合延迟,2例患者在注射期间出现月经紊乱。

结论

对于形态和解剖位置各异的瘢痕疙瘩,采用手术切除和病灶内注射曲安奈德的个体化联合治疗可实现耳廓形态重建并维持长期治疗效果。

证据级别IV:本刊要求作者为每篇文章指定证据级别。有关这些循证医学评级的完整描述,请参阅目录或作者在线指南 www.springer.com/00266 。

相似文献

1
An Effective Auricular Keloids Management Method: Excision of the Original Lesion and Postoperative Corticosteroids.一种有效的耳部瘢痕疙瘩治疗方法:切除原发病灶及术后使用皮质类固醇激素
Aesthetic Plast Surg. 2025 Jun 5. doi: 10.1007/s00266-025-04925-6.
2
Efficacy of Nd:YAG Laser and Intralesional Triamcinolone Injection Combination Therapy in the Postoperative Management of Keloids.钕钇铝石榴石激光与曲安奈德病灶内注射联合治疗在瘢痕疙瘩术后管理中的疗效
Aesthetic Plast Surg. 2025 Jan;49(2):576-583. doi: 10.1007/s00266-024-04433-z. Epub 2024 Oct 7.
3
The Combination of Tunnel Shaped Excision with Radiotherapy and Injection of Type A Botulinum Toxin in the Treatment of Auricular Keloids.隧道式切除联合放疗及A型肉毒毒素注射治疗耳廓瘢痕疙瘩
Aesthetic Plast Surg. 2025 May;49(9):2366-2372. doi: 10.1007/s00266-025-04735-w. Epub 2025 Feb 26.
4
Contour first-retrospective study of an algorithmic approach of auricular keloids.耳廓瘢痕疙瘩算法方法的首次回顾性轮廓研究。
J Cosmet Dermatol. 2023 Apr;22(4):1304-1311. doi: 10.1111/jocd.15554. Epub 2022 Dec 27.
5
Triple Surgical Technique for the Repair of Auricular Keloids: Achieving Perfect Restoration of the Ear Contour.三重手术技术修复耳廓瘢痕疙瘩:实现耳廓轮廓的完美修复。
Aesthetic Plast Surg. 2024 Oct;48(20):4086-4094. doi: 10.1007/s00266-024-04306-5. Epub 2024 Aug 14.
6
A multimodal therapeutic approach improves the clinical outcome of auricular keloid patients.多模态治疗方法改善了耳廓瘢痕疙瘩患者的临床预后。
Int J Dermatol. 2019 Jun;58(6):745-749. doi: 10.1111/ijd.14413. Epub 2019 Feb 27.
7
Individualized surgery combined with radiotherapy and triamcinolone acetonide injection for the treatment of auricular keloids.个体化手术联合放射治疗和曲安奈德注射治疗耳廓瘢痕疙瘩。
BMC Surg. 2021 May 22;21(1):256. doi: 10.1186/s12893-021-01253-9.
8
Aesthetic Reconstruction of Auricular Keloids with a Novel Hemi-keystone Flap.采用新型半耳轮皮瓣进行耳廓瘢痕疙瘩的美学重建。
Aesthetic Plast Surg. 2022 Dec;46(6):2807-2813. doi: 10.1007/s00266-022-02909-4. Epub 2022 May 12.
9
Auricular keloid management in Asian skin: Clinical outcome of intralesional excision and postoperative triamcinolone acetonide intralesional injection.亚洲人皮肤耳郭瘢痕疙瘩的治疗:病损内切除联合术后曲安奈德病损内注射的临床疗效
J Cosmet Dermatol. 2020 Nov;19(11):3041-3047. doi: 10.1111/jocd.13383. Epub 2020 Apr 16.
10
Outcome of Recurrent Auricular Keloid Treatment with a Combination of Surgical Excision and Perioperative Corticosteroid Injection.手术切除联合围手术期皮质类固醇注射治疗复发性耳廓瘢痕疙瘩的疗效
J Cutan Aesthet Surg. 2021 Oct-Dec;14(4):392-396. doi: 10.4103/JCAS.JCAS_186_20.

本文引用的文献

1
Post-operative KEloids iRradiation (POKER): does the surgery/high-dose interventional radiotherapy association make a winning hand?术后瘢痕疙瘩放疗(POKER):手术/高剂量介入放疗联合能否取得成功?
Radiol Med. 2024 Feb;129(2):328-334. doi: 10.1007/s11547-024-01756-4. Epub 2024 Jan 27.
2
Hypertrophic Scars and Keloids: Advances in Treatment and Review of Established Therapies.增生性瘢痕和瘢痕疙瘩:治疗进展及现有疗法综述
Am J Clin Dermatol. 2023 Mar;24(2):225-245. doi: 10.1007/s40257-022-00744-6. Epub 2023 Jan 20.
3
Laser therapy for treating hypertrophic and keloid scars.
激光疗法治疗增生性瘢痕和瘢痕疙瘩。
Cochrane Database Syst Rev. 2022 Sep 26;9(9):CD011642. doi: 10.1002/14651858.CD011642.pub2.
4
Combination of fractional carbon dioxide laser and topical triamcinolone vs intralesional triamcinolone for keloid treatment: A randomised clinical trial.二氧化碳点阵激光联合曲安奈德皮损内注射与单纯皮损内注射治疗瘢痕疙瘩的随机临床试验。
Int Wound J. 2022 Nov;19(7):1729-1735. doi: 10.1111/iwj.13775. Epub 2022 Feb 14.
5
Combination therapy of refractory keloid with ultrapulse fractional carbon dioxide (CO ) laser and topical triamcinolone in Asians-long-term prevention of keloid recurrence.超脉冲二氧化碳(CO )激光联合曲安奈德局部治疗亚洲人难治性瘢痕:预防瘢痕复发的长期效果。
Dermatol Ther. 2020 Nov;33(6):e14359. doi: 10.1111/dth.14359. Epub 2020 Oct 12.
6
Auricular keloid management in Asian skin: Clinical outcome of intralesional excision and postoperative triamcinolone acetonide intralesional injection.亚洲人皮肤耳郭瘢痕疙瘩的治疗:病损内切除联合术后曲安奈德病损内注射的临床疗效
J Cosmet Dermatol. 2020 Nov;19(11):3041-3047. doi: 10.1111/jocd.13383. Epub 2020 Apr 16.
7
A multimodal therapeutic approach improves the clinical outcome of auricular keloid patients.多模态治疗方法改善了耳廓瘢痕疙瘩患者的临床预后。
Int J Dermatol. 2019 Jun;58(6):745-749. doi: 10.1111/ijd.14413. Epub 2019 Feb 27.
8
Optimal High-Dose-Rate Brachytherapy Fractionation Scheme After Keloid Excision: A Retrospective Multicenter Comparison of Recurrence Rates and Complications.优化的高剂量率近距离放疗分割方案在瘢痕疙瘩切除术后的应用:复发率和并发症的回顾性多中心比较。
Int J Radiat Oncol Biol Phys. 2018 Mar 1;100(3):679-686. doi: 10.1016/j.ijrobp.2017.10.044. Epub 2017 Nov 4.
9
Advancing Keloid Treatment: A Novel Multimodal Approach to Ear Keloids.瘢痕疙瘩治疗进展:一种针对耳部瘢痕疙瘩的新型多模式方法
Dermatol Surg. 2017 Sep;43(9):1164-1169. doi: 10.1097/DSS.0000000000001145.
10
Hypofractionated electron-beam radiation therapy for keloids: retrospective study of 568 cases with 834 lesions.超分割电子束放射疗法治疗瘢痕疙瘩:568例834处病损的回顾性研究
J Radiat Res. 2015 Sep;56(5):811-7. doi: 10.1093/jrr/rrv031. Epub 2015 Jul 28.