Tsyrlina E V, Semiglazov V P, Moiseenko V M, Bornoeva T P
Neoplasma. 1985;32(4):463-7.
Cytoplasmic estrogen receptors (ER) were studied in 200 female patients with primary breast cancer. Both ER and progesterone receptors (PgR) were studied in 38 patients. Of the 200 tumors, 55% were estrogen receptor-positive, of the 38 tumors, 34.2% were progesterone receptor-positive. The level of steroid receptors was compared with some parameters characterizing the host and the tumor. It was found that the level of ER correlated with the age factors and the menstrual status. The level of ER was higher in women with adrenal or involutive pathogenetic forms of breast cancer and in women with great body weight. There was not found any relation between the level of estrogen receptors and the stage of menstrual cycle as well as between the level of estrogen receptors and the content of sex chromatin in the tumors.
对200例原发性乳腺癌女性患者的细胞质雌激素受体（ER）进行了研究。对38例患者同时研究了ER和孕激素受体（PgR）。在200个肿瘤中，55%为雌激素受体阳性，在38个肿瘤中，34.2%为孕激素受体阳性。将类固醇受体水平与一些表征宿主和肿瘤的参数进行了比较。发现ER水平与年龄因素和月经状况相关。在患有肾上腺或退化性发病形式乳腺癌的女性以及体重较大的女性中，ER水平较高。未发现雌激素受体水平与月经周期阶段之间以及雌激素受体水平与肿瘤中性染色质含量之间存在任何关系。
