Tsyrlina E V, Moiseenko V M, Boronoeva T R, Semiglazov V F
Vopr Onkol. 1984;30(4):29-33.
Estrogen receptors were studied in 108 stage I and II breast cancer patients aged 28-83. The receptors were identified in 72.6% of cases, 55.5% of tumors being estrogen receptor-positive. Estrogen receptor level and frequency in tumor were found to depend upon patient's age and menstrual function. Mean estrogen receptor levels in patients with adrenal and involutive forms of cancer, which are the most sensitive to hormone therapy were 2-3 times those in ovarian and thyroid forms, the latter being the least sensitive to hormone treatment (ovariectomy + corticosteroids). Scirrhous tumors of the breast in elderly patients were mostly estrogen receptor-positive, this pointing to favorable prognosis in this age bracket.
对108例年龄在28至83岁之间的I期和II期乳腺癌患者的雌激素受体进行了研究。在72.6%的病例中发现了这些受体，55.5%的肿瘤为雌激素受体阳性。发现肿瘤中的雌激素受体水平和频率取决于患者的年龄和月经功能。对激素治疗最敏感的肾上腺型和 involutive型癌症患者的平均雌激素受体水平是卵巢型和甲状腺型癌症患者的2至3倍，后两者对激素治疗（卵巢切除术+皮质类固醇）最不敏感。老年患者的乳腺硬癌大多为雌激素受体阳性，这表明该年龄段预后良好。 （注：“involutive”可能在医学中有特定含义，但未找到准确对应中文，暂保留原文）
