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全球马寄生虫控制指南:是共识还是困惑?

Global equine parasite control guidelines: Consensus or confusion?

作者信息

Nielsen Martin K, Pyatt Alison, Perrett Jodie, Tydén Eva, van Doorn Deborah, Pihl Tina H, Schmidt Jennifer S, von Samson-Himmelstjerna Georg, Beasley Anne, Abbas Ghazanfar, Jabbar Abdul

机构信息

Department of Animal and Veterinary Sciences, Aarhus University, Tjele, Denmark.

International Office, Veterinary Medicines Directorate, Surrey, United Kingdom.

出版信息

Int J Parasitol Drugs Drug Resist. 2025 Jun 3;28:100600. doi: 10.1016/j.ijpddr.2025.100600.

Abstract

Equine parasite control has historically been characterized by confusing and conflicting information, posing significant challenges for veterinarians and horse owners to make evidence-based decisions. Since 2012, equine parasite control guidelines have been developed and published for different parts of the world to address this situation and provide trusted sources of current guidance. At the 2024 International Equine Infectious Disease Conference in Deauville, Normandy, France, lead authors of equine parasite control guideline documents published in the USA, UK, Sweden, Denmark, the Netherlands, Australia, and Europe convened and presented their guidelines. This led to a discussion of differences and similarities between the guidelines and an effort to identify current research needs in this area. In general, all guidelines recommend a surveillance-based approach for equine parasite control, emphasizing the importance of anthelmintic resistance testing. Some guidelines have a focus on controlling Strongylus vulgaris, while others primarily focus on cyathostomins, ascarids and tapeworms. Although the same four anthelmintic drug classes are marketed in most countries, there are some differences between product portfolios available, most notably between Australia and other countries. European countries have various degrees of prescription-only restrictions on anthelmintic products, whereas products are available over the counter in Australia and the USA. Commercially available diagnostic portfolios differed somewhat between countries and affected recommendations made as well. In conclusion, the guidelines are in general agreement and are based on the same general principles. One major challenge is communicating the recommendations effectively to end-users, which should be made a priority going forward.

摘要

从历史上看,马寄生虫控制领域存在令人困惑且相互矛盾的信息,这给兽医和马主做出基于证据的决策带来了重大挑战。自2012年以来,针对世界不同地区制定并发布了马寄生虫控制指南,以应对这种情况并提供可靠的当前指导来源。在法国诺曼底迪耶普举行的2024年国际马传染病会议上,美国、英国、瑞典、丹麦、荷兰、澳大利亚和欧洲发布的马寄生虫控制指南文件的主要作者齐聚一堂并介绍了他们的指南。这引发了对各指南之间异同的讨论,并努力确定该领域当前的研究需求。总体而言,所有指南都推荐采用基于监测的方法进行马寄生虫控制,强调驱虫抗药性检测的重要性。一些指南侧重于控制普通圆线虫,而其他指南主要关注杯状线虫、蛔虫和绦虫。尽管大多数国家都销售相同的四类驱虫药物,但可用产品组合存在一些差异,澳大利亚与其他国家之间的差异最为明显。欧洲国家对驱虫产品有不同程度的仅凭处方购买限制,而在澳大利亚和美国,产品可在柜台购买。各国市售的诊断产品组合也有所不同,这也影响了所提出的建议。总之,这些指南总体上是一致的,并且基于相同的一般原则。一个主要挑战是如何有效地将这些建议传达给最终用户,这在未来应成为优先事项。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2934/12171568/815cc3871a9d/ga1.jpg

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