早产婴儿常规使用椰子油润肤治疗与1岁矫正年龄时的过敏致敏情况
Routine Emollient Therapy with Coconut Oil in Preterm Infants and Allergic Sensitization at 1-Year Corrected Age.
作者信息
Williams Terri, Weidinger Jemma, Metcalfe Jessica R, Thomas Samantha, Mountain Jenny, Currie Andrew, O'Sullivan Michael, Strunk Tobias
机构信息
Immunology Department, Perth Children's Hospital, Perth, Washington, Australia.
Neonatal Directorate, King Edward Memorial Hospital for Women, Perth, Washington, Australia.
出版信息
Neonatology. 2025 Jun 5:1-4. doi: 10.1159/000546309.
INTRODUCTION
Skin care for very and extremely preterm infant is an important and previously underappreciated topic. Coconut oil skin care for preterm infants is a promising option, but several important questions remain including the theoretical potential for allergic sensitization.
METHODS
This prospective study conducted skin prick testing and allergy questionnaires in a cohort of very preterm infants who received routine skin care with virgin coconut oil during their neonatal admission.
RESULTS
Ninety infants (median GA 28.2 weeks, median BW 1,048 g) were assessed at corrected age 15 months. A total of 8 children had positive skin prick tests to 1 or more of the most common allergens (egg, peanut, cashew, dust mite). No child was sensitized to coconut oil or extract.
CONCLUSIONS
We did not find evidence of allergic sensitization following neonatal skin care with coconut oil in children born preterm.
引言
极早产儿和超早产儿的皮肤护理是一个重要且此前未得到充分重视的话题。椰子油用于早产儿皮肤护理是一个有前景的选择，但仍存在几个重要问题，包括过敏致敏的理论可能性。
方法
这项前瞻性研究对一组在新生儿住院期间接受初榨椰子油常规皮肤护理的极早产儿进行了皮肤点刺试验和过敏问卷调查。
结果
在矫正年龄15个月时对90名婴儿（中位胎龄28.2周，中位出生体重1048克）进行了评估。共有8名儿童对1种或更多最常见过敏原（鸡蛋、花生、腰果、尘螨）的皮肤点刺试验呈阳性。没有儿童对椰子油或提取物致敏。
结论
我们没有发现早产出生儿童在新生儿期使用椰子油进行皮肤护理后出现过敏致敏的证据。
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