Won Nae Y, Wang Anna, Athay Ryan, Striley Catherine W, Cottler Linda B
Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, Florida, USA.
College of Public Health and Health Professions, University of Florida, Gainesville, Florida, USA.
Subst Use Misuse. 2025;60(11):1678-1689. doi: 10.1080/10826084.2025.2511242. Epub 2025 Jun 5.
The National Drug Early Warning System Rapid Street Reporting study monitors over 100 drugs to identify emerging use trends.
This analysis examined geographical differences in the past 12-month self-reported drug use across 20 US urban cities, identifying the three most prevalent drugs reported, excluding alcohol.
Adults (age ≥18) were surveyed in public settings using venue-intercept sampling over a weekend in each city between January 2022 and November 2023 regarding past 12-month drug use. We focused on the three most commonly reported drugs in each region. The prevalence of reported drug use by region was compared using generalized linear models with Poisson and log-link functions, adjusting for participant characteristics, time of year, and location.
Among 6,039 participants, cannabis for recreational use (50.3%), psilocybin (13.7%), and cocaine (11.0%) were the most commonly reported drugs used. While there were no regional differences in the prevalence of recreational cannabis use, psilocybin, and cocaine use were more commonly reported by people in the West versus the Midwest (adjusted prevalence ratio [aPR]=1.58, 95% confidence interval [CI]: 1.23, 2.06; aPR=1.67, 95% CI: 1.26, 2.23, respectively). We also found a higher prevalence of cocaine use reported by participants in the Northeast compared to participants in the Midwest (aPR=1.37, 95% CI: 1.00, 1.91).
Venue intercept survey method detected signals of recreational cannabis, psilocybin, and cocaine use in the 20 US urban cities visited over a weekend. Reported prevalence differed by region. This suggests that prevention messaging should be tailored to the specific US regions.
国家药物早期预警系统快速街头报告研究监测100多种药物，以识别新出现的使用趋势。
本分析研究了美国20个城市过去12个月自我报告的药物使用情况的地理差异，确定了报告的三种最普遍使用的药物（不包括酒精）。
2022年1月至2023年11月期间，在每个城市的一个周末，采用场所拦截抽样法在公共场所对成年人（年龄≥18岁）进行了调查，询问他们过去12个月的药物使用情况。我们关注每个地区报告的三种最常用药物。使用具有泊松和对数链接函数的广义线性模型比较各地区报告的药物使用患病率，并对参与者特征、一年中的时间和地点进行调整。
在6039名参与者中，用于娱乐的大麻（50.3%）、裸盖菇素（13.7%）和可卡因（11.0%）是报告使用最多的药物。虽然娱乐性大麻使用的患病率没有地区差异，但与中西部地区相比，西部地区的人更常报告使用裸盖菇素和可卡因（调整患病率比[aPR]=1.58，95%置信区间[CI]：1.23，2.06；aPR=1.67，95%CI：1.26，2.23）。我们还发现，与中西部地区的参与者相比，东北部地区的参与者报告的可卡因使用率更高（aPR=1.37，95%CI：1.00，1.91）。
场所拦截调查方法在一个周末走访的美国20个城市中检测到了娱乐性大麻、裸盖菇素和可卡因使用的信号。报告的患病率因地区而异。这表明预防信息应针对美国的特定地区进行定制。
