Es-Sahli Fatima Zahra, Sbai Achraf Amine, Haloui Anass, Benfadil Drissia, Bennani Amal, Lachkar Azzedine, Tsen Adil Abdnbi, Ayoubi Fahd El
Department of Ear Nose and Throat, Mohammed VI University Hospital, Oujda, Morocco.
Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed the First University, Oujda, Morocco.
Radiol Case Rep. 2025 May 12;20(8):3710-3714. doi: 10.1016/j.radcr.2025.04.071. eCollection 2025 Aug.
Adenoid cystic carcinoma (ACC) is a rare malignant neoplasm arising in both major and minor salivary glands. It represents approximately 1% of all head and neck cancers and about 10% of salivary gland tumors. Laryngeal adenoid cystic carcinoma (LACC) is a rare entity that most frequently arises in the subglottic region. It is characterized by slow progression, perineuronal invasion, frequent local recurrences and delayed distant metastasis. Surgical resection remains the gold standard for the treatment of ACC; however, the role of adjuvant radiotherapy and prophylactic neck dissection remains uncertain and is widely debated in the literature. This case report describes a 60-year-old male patient who presented with progressive dysphagia and worsening dyspnea. Clinical evaluation, including computed tomography (CT), revealed a lesion involving the left glottic and supraglottic regions. Biopsy obtained via direct laryngoscopy confirmed the diagnosis of laryngeal adenoid cystic carcinoma (LACC). The patient subsequently underwent total laryngectomy with adjuvant radiotherapy.
腺样囊性癌（ACC）是一种罕见的恶性肿瘤，发生于大、小唾液腺。它约占所有头颈癌的1%，占唾液腺肿瘤的10%左右。喉腺样囊性癌（LACC）是一种罕见的病变，最常发生于声门下区。其特点是进展缓慢、神经周围浸润、频繁局部复发和远处转移延迟。手术切除仍然是ACC治疗的金标准；然而，辅助放疗和预防性颈清扫的作用仍不确定，在文献中存在广泛争议。本病例报告描述了一名60岁男性患者，表现为进行性吞咽困难和呼吸困难加重。包括计算机断层扫描（CT）在内的临床评估显示，病变累及左声门和声门上区。通过直接喉镜检查获取的活检证实了喉腺样囊性癌（LACC）的诊断。患者随后接受了全喉切除术及辅助放疗。
